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The role of fibrillin and microfibril binding proteins in elastin and elastic fibre assembly
- A. Godwin, Mukti Singh, Michael P Lockhart-Cairns, Yasmene F. Alanazi, S. Cain, C. Baldock
- Medicine, ChemistryMatrix biology : journal of the International…
- 18 June 2019
Fibrillin microfibrils mediate cell signalling via integrin and syndecan receptors, and microfibils sequester transforming growth factor (TGF)β family growth factors within the matrix to provide a tissue store which is critical for homeostasis and remodelling.
Autosomal Recessive Cutis Laxa 1C Mutations Disrupt the Structure and Interactions of Latent TGFβ Binding Protein-4
- Yasmene F. Alanazi, Michael P Lockhart-Cairns, S. Cain, T. Jowitt, A. Weiss, C. Baldock
- MedicineFrontiers in Genetics
- 3 September 2021
The results suggest thatLTBP4 mutations contribute to ARCL1C by disrupting the structure and interactions of LTBP4 which are essential for elastogenesis in a range of mammalian connective tissues.
Computing Correlation among the Graphs under Lexicographic Product via Zagreb Indices
<jats:p>A topological index (TI) is a numerical descriptor of a molecule structure or graph that predicts its different physical, biological, and chemical properties in a theoretical way avoiding the…