Yared Nigussie Demssie

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Spindle cell oncocytoma (SCO) is a rare non-functioning tumour of the pituitary which has just been formally recognized as a distinct entity by the 2007 WHO classification of brain tumours. We report a case of SCO who presented with symptoms of visual blurring, weight loss, intermittent vomiting and excessive tiredness of several months duration.(More)
The recent evidence-based shift towards an algorithm of early initiation and aggressive titration of insulin therapy in the management of type 2 diabetes requires the use of an effective insulin formulation that is both safe and acceptable to patients and physicians alike. The advent of the long-acting insulin analogues, insulin detemir and glargine, in the(More)
OBJECTIVE To assess metabolic outcomes in obese people with type 2 diabetes (T2D) in the first year following gastric bypass surgery. SUBJECTS AND METHODS Forty-nine obese patients with T2D who had undergone gastric bypass surgery 12 or more months previously were identified. Body weight and glycosylated haemoglobin (HbA(1c)) pre-operatively and 3, 6 and(More)
Hyponatraemia (serum sodium level < 135 mmol/litre) is the most common electrolyte abnormality among hospitalized patients. A prevalence rate as high as 15-30% has been reported among patients admitted to acute and intensive care units (Hoorn et al, 2004; Jaber et al, 2006). Evidence suggests an increase in mortality associated with even a mild degree of(More)
The role of tight glycaemic control in reducing cardiovascular events and mortality in type 2 diabetes has not yet been firmly established. Recent clinical trials have yielded unexpected outcomes. This review summarizes the background and outcome of these trials and the implications for management of glycaemia in type 2 diabetes.
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