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Regularized linear discriminant analysis and its application in microarrays.
TLDR
Through both simulated data and real life data, it is shown that this method performs very well in multivariate classification problems, often outperforms the PAM method and can be as competitive as the support vector machines classifiers.
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Regularized Discriminant Analysis and Its Application in Microarrays
TLDR
These SCRDA methods generalize the idea of the nearest shrunken centroids of Prediction Analysis of Microarray into the classical discriminant analysis and perform uniformly well in the multivariate classification problems, especially outperform the currently popular PAM.
Global transcriptional response to interferon is a determinant of HCV treatment outcome and is modified by race
TLDR
Both treatment outcome and race are associated with different transcriptional responses to interferon treatment outcomes, and key factors affecting the outcome of IFN‐α therapy are likely to act at the JAK‐STAT pathway that controls transcription of downstream ISGs.
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Microarray analysis of differentially expressed genes in vaginal tissues from women with stress urinary incontinence compared with asymptomatic women.
TLDR
Genes involved in elastin metabolism were differentially expressed in vaginal tissue from women with SUI, suggesting thatElastin remodelling may be important in the molecular aetiology of SUI.
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Microarray Analysis Reveals Differences in Gene Expression of Circulating CD8+ T Cells in Melanoma Patients and Healthy Donors
TLDR
The results suggest the possible engagement of an alternative apoptosis pathway in circulating T cells from cancer patients and found that these 10 genes provide a much better discrimination between melanoma and healthy T cells as compared with a classifier built uniquely with classical apoptosis-related genes.
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The Association between Parental Marital Satisfaction and Adolescent Prosocial Behavior in China: A Moderated Serial Mediation Model
Parental marital satisfaction is a well-established protective factor for prosocial behavior in adolescents, yet the parental socialization of adolescent prosocial behavior is limited in Chinese…
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Peer support mediates sex differences in self-esteem and problem behaviors among children: Does parental migration make a difference?
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