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High Prevalence of Vitamin D Insufficiency in China: Relationship with the Levels of Parathyroid Hormone and Markers of Bone Turnover
There is a lack of large-scale studies on vitamin D status and its relationship to parathyroid hormone (PTH) and bone turnover markers in adults living in Shanghai. The objectives were to determineExpand
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The identification of novel mutations in COL1A1, COL1A2, and LEPRE1 genes in Chinese patients with osteogenesis imperfecta
Dominant inheritance of osteogenesis imperfecta (OI) is caused by mutations in COL1A1 or COL1A2, the genes that encode type I collagen, and CRTAP, LEPRE1, PPIB, FKBP10, SERPINH1, and SP7 mutationsExpand
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Association between VDR and ESR1 gene polymorphisms with bone and obesity phenotypes in Chinese male nuclear families
AbstractAim:The goal of this study was to determine whether polymorphisms in the vitamin D receptor (VDR) and estrogen receptor alpha (ESR1) genes are associated with variations of peak bone mineralExpand
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  • Open Access
Lean mass predicts hip geometry and bone mineral density in chinese men and women and age comparisons of body composition.
  • W. Hu, H. Zhang, +7 authors Z. Zhang
  • Medicine
  • Journal of clinical densitometry : the official…
  • 1 October 2012
Previous studies have suggested that changes in hip geometry increase the risk of hip fracture. The aim of this study was to identify whether body composition were associated with hip geometry orExpand
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Serum osteocalcin levels are inversely associated with plasma glucose and body mass index in healthy Chinese women
Aim:Osteocalcin, a biochemical marker of bone formation, has been suggested to be involved in the regulation of energy metabolism. The aim of this study was to investigate the possible associationExpand
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  • Open Access
A novel VCP mutation as the cause of atypical IBMPFD in a Chinese family.
INTRODUCTION Inclusion-body myopathy (IBM) with Paget's disease of bone (PDB) and frontotemporal dementia (FTD), designated as IBMPFD, is a rare, autosomal dominant disorder (MIM 605382). IBMPFD isExpand
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Susceptibility genes for osteoporotic fracture in postmenopausal chinese women
  • C. Wang, Z. Zhang, +10 authors Z. Zhang
  • Medicine, Biology
  • Journal of bone and mineral research : the…
  • 1 December 2012
To identify the susceptibility genes for osteoporotic fracture in postmenopausal Chinese women, a two‐stage case‐control association study using joint analysis was conducted in 1046 patients withExpand
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Association of serum 25-hydroxyvitamin D with insulin resistance and β-cell function in a healthy Chinese female population
Aim:To assess associations of the serum level of 25-hydroxyvitamin D with insulin resistance and β-cell function in a healthy Chinese female population.Methods:This cross-sectional study includedExpand
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  • Open Access
Identification of the mutations in the tissue-nonspecific alkaline phosphatase gene in two Chinese families with hypophosphatasia.
BACKGROUND AND AIMS Hypophosphatasia is a genetic disorder characterized by defective bone and tooth mineralization and a deficiency of serum and bone alkaline phosphatase activity. To date, fewExpand
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Early onset Paget's disease of bone caused by a novel mutation (78dup27) of the TNFRSF11A gene in a Chinese family
AbstractAim:A previous study showed that individuals of Japanese descent affected by early onset familial Paget's disease of bone (PDB) carried a 27-bp duplication at position 75 (75dup27) in theExpand
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