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Most real-world recommender services measure their performance based on the top-N results shown to the end users. Thus, advances in top-N recommendation have far-ranging consequences in practical applications. In this paper, we present a novel method, called Collaborative Denoising Auto-Encoder (CDAE), for top-N recommendation that utilizes the idea of(More)
Customized semantic query answering, personalized search, focused crawlers and localized search engines frequently focus on ranking the pages contained within a subgraph of the global Web graph. The challenge for these applications is to compute PageRank-style scores efficiently on the subgraph, i.e., the ranking must reflect the global link structure of(More)
Although a lower methylation level of whole genome has been demonstrated in Tetralogy of Fallot (TOF) patients, little is known regarding changes in specific gene DNA methylation profiles and the possible associations with TOF. In current study, the promoter methylation statuses of congenital heart defect (CHD) candidate genes were measured in order to(More)
Dentin sialophosphoprotein (DSPP) is an extracellular matrix, typically dentin- and bone-specific gene, which plays an important role in dentin mineralization and tooth development. Adipose-derived stromal cells (ADSCs) are considered to contain a group of pluripotent mesenchymal stem cells which are capable of mineralization either in vitro or in vivo. In(More)
Authority flow techniques like PageRank and ObjectRank can provide personalized ranking of typed entity-relationship graphs. There are two main ways to personalize authority flow ranking: Node-based personalization, where authority originates from a set of user-specific nodes; edge-based personalization, where the importance of different edge types is(More)
BACKGROUND Clinical and laboratory data available on patients with Ebola virus disease (EVD) remain extremely limited. We summarized the clinical characteristics of patients with EVD and analyzed the factors related to their death. METHODS Patients admitted for care at the Freetown China-Sierra Leone Friendship Hospital during 1 October-14 November 2014(More)
Methylation levels of long interspersed nucleotide elements (LINE-1) are representative of genome-wide methylation status and play an important role in maintaining genomic stability and gene expression. To derive insight into the association between genome-wide methylation status and tetralogy of fallot (TOF), we compared the methylation status of LINE-1(More)
Styryl dyes (also referred to as FM dyes) become highly fluorescent upon binding to membranes and are often used to study synaptic vesicle recycling in neurons. To date, however, no direct comparisons of the fluorescent properties, or time-resolved (millisecond) measurements of dye-membrane binding and unbinding reactions, for all members of this family of(More)
Accurate segmentation of the prostate in computed tomography (CT) images is important in image-guided radiotherapy; however, difficulties remain associated with this task. In this study, an automatic framework is designed for prostate segmentation in CT images. We propose a novel image feature extraction method, namely, variant scale patch, which can(More)