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  • Panagis Filippakopoulos, Jun Qi, Sarah Picaud, Yao Shen, William B. Smith, Oleg Fedorov +19 others
  • 2010
Epigenetic proteins are intently pursued targets in ligand discovery. So far, successful efforts have been limited to chromatin modifying enzymes, or so-called epigenetic 'writers' and 'erasers'. Potent inhibitors of histone binding modules have not yet been described. Here we report a cell-permeable small molecule (JQ1) that binds competitively to(More)
In this paper, we present a shortest-path-based algorithm, called local shortest path(LSP), for topology control in wireless multihop networks. In this algorithm, each node locally computes the shortest paths connecting itself to nearby nodes based on some link weight function, and then it selects all the second nodes on the shortest paths as its logical(More)
—A Genetic Algorithm (GA) is a heuristic to find exact or approximate solutions to optimization and search problems within an acceptable time. We discuss GAs from an architectural perspective, offering a general analysis of GAs on multi-core CPUs and on GPUs, with solution quality considered. We describe widely-used parallel GA schemes based on(More)
The heavily-threaded data processing demands of streaming multiprocessors (SM) in a GPGPU require a large register file (RF). The fast increasing size of the RF makes the area cost and power consumption unaffordable for traditional SRAM designs in the future technologies. In this paper, we propose to use embedded-DRAM (eDRAM) as an alternative in future(More)
In this paper, we propose ADTreesLogit, a model that integrates the advantage of ADTrees model and the logistic regression model, to improve the predictive accuracy and interpretability of existing churn prediction models. We show that the overall predic-tive accuracy of ADTreesLogit model compares favorably with that of TreeNet®, a model which won the Gold(More)
A low-cost Video Image Detection Systems (VIDS) is introduced. Using video analytics, the system can count the number of vehicles making a left (or right) turn at an unseen intersection plus collect statistics on other traffic conditions. Other functionality can be added. Two cameras with non-overlapping views were used as the information source. Between(More)