Yao-Huei Huang

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Ionizing radiation induces cellular senescence to suppress cancer cell proliferation. However, it also induces deleterious bystander effects in the unirradiated neighboring cells through the release of senescence-associated secretory phenotypes (SASPs) that promote tumor progression. Although autophagy has been reported to promote senescence, its role is(More)
Securin overexpression correlates with poor prognosis in various tumours. We have previously shown that securin depletion promotes radiation-induced senescence and enhances radiosensitivity in human cancer cells. However, the underlying molecular mechanisms and the paracrine effects remain unknown. In this study, we showed that radiation induced senescence(More)
The cutting stock problem (CSP) is a critical issue in the manufacturing of thin film transistor liquid crystal display (TFT-LCD) products. Two manufacturing processes are utilized in this industry: (1) various TFT-LCD plates are cut from a glass substrate based on cutting patterns, and (2) the number of glass substrates required to satisfy customer(More)