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  • Yang Han, Dong Guo, Yao Chen, Yu Chen, Zhi-Rong Tan, Hong-hao Zhou
  • Medicine
  • European Journal of Clinical Pharmacology
  • 2009 (First Publication: 1 June 2009)
  • PurposeTo investigate the effects of silymarin on the pharmacokinetics of losartan and its active metabolite E-3174 and its relationship with CYP2C9 genotypes.MethodsTwelve healthy adult men of knownContinue Reading
  • Yao Chen, Peng Xiao, +8 authors Hong-hao Zhou
  • Medicine
  • Clinical and experimental pharmacology…
  • 2009 (First Publication: 1 August 2009)
  • 1. Quercetin, one of the most abundant natural flavonoids, has been reported to modulate the activity of several drug-metabolising enzymes. The aim of the present study was to investigate the effectsContinue Reading