Yanyan Huang

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To infect an animal host, Salmonella enterica serovar Typhimurium must penetrate the intestinal epithelial barrier. This process of invasion requires a type III secretion system encoded within Salmonella pathogenicity island I (SPI1). We found that a mutant with deletions of the acetate kinase and phosphotransacetylase genes (ackA-pta) was deficient in(More)
Previous studies in patients with a major depressive disorder show functional abnormalities in the medial frontal cortex. Functional and structural abnormalities in patients with post-stroke depression (PSD) are not well studied. The major goals of this study were to determine the biochemical abnormalities that occur in PSD and to assess the effect of(More)
Using DNA microarrays, we generated both mRNA and miRNA expression data from 6 non-small cell lung cancer (NSCLC) tissues and their matching normal control from adjacent tissues to identify potential miRNA markers for diagnostics. We demonstrated that hsa-miR-96 is significantly and consistently up-regulated in all 6 NSCLCs. We validated this result in an(More)
Recent findings suggests that PDE4D (gene encoding phosphodiesterase 4D) is a stroke-related gene in the Icelandic population, but it is still very controversial as to whether it is a susceptible gene for stroke in other populations. In the present study, we attempted to explore the role of the gene in the pathogenesis of stroke in the Chinese Han(More)
According to our previous study of the M genes of H9N2 avian influenza viruses (AIV) in infected chickens, A/Quail/Hong Kong/G1/97 (G1 97)-like M genes newly emerged in northern and eastern China in addition to the existing A/chicken/Hong Kong/Y280/97 (Y280)-like lineage M genes. To systematically track the genesis and evolution of H9N2 viruses in this(More)
Goos-Hänchen (GH) shift of a transverse-magnetic (TM) wave reflected from a semi-infinite anisotropic metamaterial consisting of aligned metallic nanowires in a dielectric matrix is investigated. Based on Bruggeman effective medium theory, we obtain the conditions for realizing the negative refraction, which are dependent on both the incident wavelength and(More)
BACKGROUND Meropenem is a carbapenem with a broad spectrum of activity against beta-lactamase-producing organisms. Valproic acid is widely used in the treatment of generalized tonic-clonic and partial seizures. Concomitant administration of meropenem and valproic acid reportedly leads to a rapid decline in serum concentrations of valproic acid, which is(More)
The purpose of this study was to judge the clinical value of minimally invasive stereotactic puncture and thrombolysis therapy (MISPTT) for acute intracerebral hemorrhage (ICH). A randomized control clinical trial was undertaken. According to the enrollment criteria, 122 acute ICH cases were analyzed, of which 64 cases received MISPTT (MISPTT group, MG) and(More)
OBJECTIVE To study the effect of imaging parameters on the contrast of T1 weighted SPACE (Sampling Perfection with Application optimized Contrast using different angle Evolutions, a 3D TSE variant) at 3 T for high resolution imaging of intracranial plaques before contrast and with post-gadolinium induced enhancement, and evaluate its relevance to patients(More)
OBJECTIVE In order to study the role of porcine CD151 in infection of porcine cells by porcine reproductive and respiratory syndrome virus (PRRSV), we established a porcine CD151 transgenic PK-15 cell line. METHODS The full-length complementary DNA (cDNA) for porcine CD151 was amplified from porcine alveolar macrophages by reverse transcription-polymerase(More)