Yanqing Pan

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BACKGROUND Primary spontaneous pneumothorax (PSP) or pulmonary cysts is one of the manifestations of Birt-Hogg-Dube syndrome (BHDS) that is caused by heterozygous mutations in FLCN gene. Most of the mutations are SNVs and small indels, and there are also approximately 10 % large intragenic deletions and duplications of the mutations. These molecular(More)
BACKGROUND Surgery is the best treatment for early and middle stage non-small cell lung cancer. The aim of this study is to summarize the experience of bronchial sleeve mortality lobectomy and carinal resection in the treatment of 92 patients with central lung cancer from January, 1996 to May, 2010. METHODS A total of 92 patients with central lung cancer(More)
Primary spontaneous pneumothorax (PSP) is a significant clinical problem, affecting tens of thousands patients annually. Germline mutations in the FLCN gene have been implicated in etiology of familial PSP (FPSP). Most of the currently identified FLCN mutations are small indels or point mutations that detected by Sanger sequencing. The aim of this study was(More)
When a vascular shunt is present, major lung resection may cause acute right heart failure. We report a case of right lung cancer with ipsilateral partial anomalous pulmonary venous return (PAPVR) and absent right upper lobe managed by pneumonectomy. A 48-year-old former smoker was diagnosed as right lung cancer; chest computed tomography (CT) revealed an(More)
Tracheomalacia is a disorder of the large airways that is often caused by a large anterior mediastinal mass. This study describes 7 patients who underwent controlled trachea suspension as a surgical intervention to prevent severe tracheomalacia and provide potent relief of airway symptoms. All patients recovered well. The results demonstrate this procedure(More)
BACKGROUND Our study aims to determine the value of bronchial anastomosis using complete continuous suture. METHODS Six patients diagnosed with central lung carcinoma who were candidates for right-sided sleeve lobectomy and underwent sleeve resection of the right upper lobe by thoracoscopic surgical procedure. RESULTS The mean surgical time was 182 min(More)
Ultrasonography can be performed as an adjunct to aid in the localization of small nodules. We describe 25 patients with computed tomographic evidence of peripheral pulmonary lesions (PPLs) who underwent bronchoscopy with endobronchial ultrasonography (EBUS) for localization. The results demonstrate that methylene blue injection with radial EBUS is a simple(More)
Germline mutations in FLCN are responsible for ~10% of patients with primary spontaneous pneumothorax (PSP), characterized by multiple lung cysts in the middle/lower lobes and recurrent pneumothorax. These clinical features are also observed in a substantial portion of patients with sporadic PSP exhibiting no FLCN coding mutations. To assess the potential(More)
A partial anomalous pulmonary venous connection (PAPVC) is an uncommon congenital anomaly. This report documents the case of a 48-year-old man with PAPVC which was incidentally discovered with right lung cancer and absence of right upper lobe. Right pneumonectomy was successfully performed, and the patient had an uneventful postoperative course.(More)
A 13-year-old boy with a primitive neuroectodermal tumor of the chest wall is presented. After four cycles of chemotherapy, a computed tomography scan of his chest showed a larger mass invading the left upper lobe of the lung. He underwent resection of the left chest wall from the left fourth to sixth ribs, including the tumor, combined with left upper(More)