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Severe Acute Pancreatitis in China: Etiology and Mortality on 1976 Patients
TLDR
In this retrospective study, biliary tract disease was the main etiologic factor of severe acute pancreatitis in China and the highest mortality occurred in severe idiopathic pancreatitis, and there was no clear relationship between mortality and age.
Molecular Characterization of a Ryanodine Receptor Gene in the Rice Leaffolder, Cnaphalocrocis medinalis (Guenée)
TLDR
This study isolated a full-length RyR cDNA from Cnaphalocrocis medinalis, an important rice pest throughout Southeast Asia, and found that two alternative splicing sites were identified in the CmRyR gene, one of which was located in the central part of the predicted second SPRY domain.
Effects of phytochemicals sulforaphane on uridine diphosphate-glucuronosyltransferase expression as well as cell-cycle arrest and apoptosis in human colon cancer Caco-2 cells.
TLDR
The chemopreventive effects of SFN on human colon cancer Caco-2 cells may have been partly attributed to Nrf2-mediated UGT1A induction and apoptosis induction, and these studies provided theoretic and experimental basis for clinical application ofSFN to human Colon cancer prevention.
Vasoplegia after heart transplantation: outcomes at 1 year.
TLDR
Although vasoplegia syndrome was associated with an increase in perioperative morbidity, including greater mechanical ventilation time and hospital length of stay, no significant differences in survival or allograft rejection at 1 year was demonstrated.
High miR-454-3p expression predicts poor prognosis in hepatocellular carcinoma
TLDR
Overexpression of miR-454-3p may be a significant and independent predictor of poor prognosis in HCC patients and was associated with patient survival, G3/G4 staging, III/IV staging and T staging.
Systemic In Silico Screening in Drug Discovery for Coronavirus Disease (COVID-19) with an Online Interactive Web Server
  • Chi Xu, Z. Ke, +15 authors Bing Liu
  • Computer Science, Medicine
    J. Chem. Inf. Model.
  • 11 August 2020
TLDR
This study provides an initial evaluation of current drug candidates from various reports using systemic in silico drug screening based on structures of viral proteins and human ACE2 receptor and builds an interactive online platform for browsing these results.
PES1 In Liver Cancer: A Prognostic Biomarker With Tumorigenic Roles
TLDR
PES1 was highly expressed in liver cancer tissues, served as a diagnostic marker, and correlated with poor overall survival (OS) and relapse-free survival (RFS) in patients, and PES1 may be a novel diagnostic and prognostic bio-marker and a promising therapeutic target in Liver cancer.
Prevention of Severe Acute Pancreatitis With Octreotide in Obese Patients: A Prospective Multi-Center Randomized Controlled Trial
TLDR
Intravenous administration of octreotide for 72 hours in the early stage of AP could prevent the development of SAP effectively in obese patients by raising plasma somatostatin to a normal level and reducing circulating cytokines.
Apelin as a novel drug for treating preeclampsia
TLDR
Of note, apelin treatment significantly ameliorated the symptoms of preeclampsia, improved the impaired endothelial nitric oxide synthase/nitric oxide signaling and attenuated activation of oxidative stress in RUPP rats, suggesting that apelin may be a potential agent for preventing and treating preeClampsia.
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