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The androgen receptor (AR) is important for prostate cancer development and progression. Genome-wide mapping of AR binding sites in prostate cancer has found that the majority of AR binding sites are located within non-promoter regions. These distal AR binding regions regulate AR target genes (e.g. UBE2C) involved in prostate cancer growth through chromatin(More)
Phosphoprotein-binding domains (PPBDs) mediate many important cellular and molecular processes. Ten PPBDs have been known to exist in the human proteome, namely, 14-3-3, BRCT, C2, FHA, MH2, PBD, PTB, SH2, WD-40 and WW. PepCyber:P approximately PEP is a newly constructed database specialized in documenting human PPBD-containing proteins and PPBD-mediated(More)
Multireceiver encryption enables a sender to encrypt a message and transmit the ciphertext to a set of authorized users while no one outside this set can decrypt the message , which is known as an efficient protocol to achieve a secure multicast data communication among multiple authorized users. In this work, we construct two identity-based multireceiver(More)
Recent studies have paid much attention on the safety of bevacizumab as adjuvant chemotherapy for metastatic colorectal cancer. The aim of this meta-analysis was to study the efficacy and safety of bevacizumab in combination with irinotecan, bolus followed by infusional 5-fluorouracil, and leucovorin (FOLFIRI) and, irinotecan, bolus fluorouracil, leucovorin(More)
1. ABSTRACT Variable selection for generalized linear models has been a challenge in SAS® as current packages are either limited to a small scope of models or the searching algorithm still focuses on forward/backward/stepwise that biases parameter estimation ([1]). The proposed macro VarSel_PGA was built upon such need. It utilizes the Genetic Algorithm(More)
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