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Grape seed extract inhibits the growth and pathogenicity of Staphylococcus aureus by interfering with dihydrofolate reductase activity and folate-mediated one-carbon metabolism.
TLDR
GSE might serve as an effective natural alternative for the control of food poisoning caused by S. aureus with proper safety measure, indicated that GSE-induced perturbation in folate-mediated one-carbon metabolism has more profound impact on methionine cycle than on thymidine monophosphate synthesis. Expand
Purification, Characterization and Inhibition of Alanine Racemase from a Pathogenic Strain of Streptococcus iniae
TLDR
The 50% inhibitory concentrations (IC50) values and antibiotic activity of two alanine racemase inhibitors were determined and found to be effective against both Gram-positive and Gram-negative bacteria employed in this study. Expand
Cloning, Biochemical Characterization and Inhibition of Alanine racemase from Streptococcus iniae
TLDR
The 50% inhibitory concentrations (IC50) values and antibiotic activity of two alanine racemase inhibitors, were determined and found to be effective against both gram positive and gram negative bacteria employed in this study. Expand