Yanliang Zhang

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Semiconductive nanowire-based biosensors are capable of label-free detection of biological molecules. Nano-FET (field-effect transistor) biosensors exhibiting high sensitivities toward proteins, nucleic acids, and viruses have been demonstrated. Rational device design methodologies, particularly those based on theoretical predictions, were reported.(More)
Obtaining thermoelectric materials with high figure of merit ZT is an exacting challenge because it requires the independent control of electrical conductivity, thermal conductivity and Seebeck coefficient, which are often unfavourably coupled. Recent works have devised strategies based on nanostructuring and alloying to address this challenge in thin(More)
Vision guided automatic cell injection system has become increasingly important in the past ten years. The existing cell injection systems mainly deal with large cells with size bigger than 40 micrometers. However, when dealing with small cells, the internal and external disturbances presented in the system may affect the success rate of injections(More)
ZnO is a promising high figure-of-merit (ZT) thermoelectric material for power harvesting from heat due to its high melting point, high electrical conductivity σ, and Seebeck coefficient α, but its practical use is limited by a high lattice thermal conductivity κ(L). Here, we report Al-containing ZnO nanocomposites with up to a factor of 20 lower κ(L) than(More)
In this paper, a new calibration method for piezoelectric actuator-based vision guided cell microinjection system is proposed. This method puts all the parameterspsila uncertainties in a lumped rotational matrix instead of classifying the parameters into extrinsic and intrinsic categories. The difference between the measured and nominal output is assumed to(More)
Conventional camera calibration that utilizes the extrinsic and intrinsic parameters of the camera and the objects has certain limitations for micro-level cell operations due to the presence of hardware deviations and external disturbances during the experimental process, thereby invalidating the extrinsic parameters. This invalidation is often neglected in(More)
Making changes of cells function by regulating the external mechanical environment is one of the major interests in the mechanobiology field. Based on extensive studies, force at nano-to-micro newton and geometric shape changes at nano-to-micrometer are the physical stimuli that can be sensed by cells. It has been postulated that controllable cell responses(More)
Antimony telluride has a low thermoelectric figure of merit (ZT < ∼0.3) because of a low Seebeck coefficient α arising from high degenerate hole concentrations generated by antimony antisite defects. Here, we mitigate this key problem by suppressing antisite defect formation using subatomic percent sulfur doping. The resultant 10-25% higher α in bulk(More)
Changes in the bioactivity of a protein after being adsorbed on a material surface may result from conformational changes of the protein. Unfortunately, however, direct evidence of such conformational changes of proteins adsorbed on a flat material surface is sparse so far. This is because probing the conformation of an adsorbed protein on material(More)