Yanli Ma

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The paper presents a genetic algorithm based on wavelet threshold medical image denoising method. Theoretically analyses the principle of wavelet threshold denoising, the improved threshold function is proposed. Using genetic algorithm combined with clustering histogram of the image information are used to get the optimal threshold, the calculation without(More)
Targeted drug delivery is important in cancer therapy to decrease the systemic toxicity resulting from nonspecific drug distribution and to enhance drug delivery efficiency. We have developed an aptamer-based DNA dendritic nanostructure as a multifunctional vehicle for targeted cancer cell imaging and drug delivery. The multifunctional DNA dendrimer is(More)
BACKGROUND The human SLC25A13 gene encodes citrin, the liver-type mitochondrial aspartate/glutamate carrier isoform 2 (AGC2), and SLC25A13 mutations cause citrin deficiency (CD), a disease entity that encompasses different age-dependant clinical phenotypes such as Adult-onset Citrullinemia Type II (CTLN2) and Neonatal Intrahepatic Cholestasis caused by(More)
Aflatoxin B1 (AFB1) is a potent carcinogen that can induce hepatocellular carcinoma. AFB1-8,9-exo-epoxide, one of AFB1 metabolites, acts as a mutagen to react with DNA and induce gene mutations, including the tumor suppressor p53. In addition, AFB1 reportedly stimulates IGF receptor activation. Aberrant activation of IGF-I receptor (IGF-IR) signaling is(More)
A simple and efficient cryopreservation protocol using encapsulation-dehydration was established for in vitro-grown shoot-tips of apple ‘Gala’ (Malus × domestica Borkh.). Shoot-tips, of 2.0 mm in length and with 5–6 leaf primordia, excised from 4-week-old shoot stock cultures, without cold-hardening, were encapsulated into beads, each being about 5 mm in(More)
A facile precipitation method has been developed to synthesize ZnO with [bis(2-aminoethyl)amino]methyl lignin (lignin amine) that is chemically modified from low-cost pulp industrial lignin. The obtained ZnO crystallites have been characterized to exhibit a hexagonal wurtzite structure, and their sizes have been determined at ca. 24 nm (mean value). These(More)
OBJECTIVE To analysis the acoustic characteristics in patients with unilateral arytenoid dislocation and unilateral vocal fold paralysis, and evaluate the application value of acoustic analysis technique in these two diseases. METHOD The voice signals of sustained vowel /a/ were measured using the software MDVP in 50 healthy adults and 67 patients with(More)
To identify genes that regulate the dynamics of lipid droplet (LD) size, we have used the genetically tractable model organism Caenorhabditis elegans, whose wild-type LD population displays a steady state of size with an upper limit of 3 μm in diameter. From a saturated forward genetic screen of 6.7 × 10(5) mutagenized haploid genomes, we isolated 118(More)
AIMS To assess the language function of children with benign epilepsy with centrotemporal spikes (BECTS), and investigate associated risk factors. METHODS The language function of 63 children with BECTS and 30 healthy controls was assessed using the language subtest of the Chinese version of the Wechsler Intelligence Scale for Children (C-WISC). Multiple(More)
Reactive nodular fibrous pseudotumor (RNFP) is a tumor‑like lesion that is characterized by reactive fibro-blast/myofibroblast proliferation within collagenic hyalinized stroma, due to its association with injury or inflammation. The current study describes the case of a 60-year-old female with a history of abdominal surgery and abdominal pain. Upon(More)