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The air-dried aerial parts of Lavandula angustifolia Mill, a traditional Uygur herbal drug, is used as resuscitation-inducing therapy to treat neurodisfunctions, such as stroke. This study was designed to assess the neuroprotective effects of lavender oil against ischemia/reperfusion (IR) injury in mice. Focal cerebral ischemia was induced by the(More)
Alzheimer's disease (AD) is the most common form of dementia. Oxidative stress is one of the earliest events in the neurological and pathological changes of AD. l-3-n-butylphthalide (l-NBP), an anti-cerebral ischemia agent, has been shown a potential in AD treatment. In this study, we investigated the neuroprotective effect of l-NBP on hydrogen peroxide(More)
L-3-n-butylphthalide (L-NBP), an extract from seeds of Apium graveolens Linn (Chinese celery), has been shown to have neuroprotective effects on cerebral ischemic, vascular dementia and amyloid-β (Aβ)-induced animal models by inhibiting oxidative injury, neuronal apoptosis and glial activation, regulating amyloid-β protein precursor (AβPP) processing and(More)
Potassium 2-(1-hydroxypentyl)-benzoate (dl-PHPB) has been shown to have potent neuroprotective effects, such as reducing the infarct volume and improving neurobehavioral deficits in the transient focal cerebral ischemic rat model. The present study is to evaluate the neuroprotective effect of dl-PHPB on hydrogen peroxide (H(2)O(2))-induced apoptosis and the(More)
WT human APP 695 ; SAMP8, senescence-accelerated mouse prone 8; PKB, protein kinase B; ADAM, A member of the disintegrin and metalloprotease; IHC, Immunohistochemistry. This article has not been copyedited and formatted. The final version may differ from this version. ABSTRACT Alzheimer' disease (AD) is a progressive neurodegenerative disorder characterized(More)
Amyloid precursor protein (APP) is cleaved by α-secretase, within the amyloid-β (Aβ) sequence, resulting in the release of a secreted fragment (αAPPs) and precluding Aβ production. We investigated the effects of a promising anti-AD new drug, l-3-n-butylphthalide (L-NBP), on APP processing and Aβ generation in neuroblastoma SK-N-SH cells overexpressing(More)
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by amyloid-β (Aβ) deposition and neurofibrillary tangles. Dl-PHPB [potassium 2-(1-hydroxypentyl)-benzoate], has been shown to have neuroprotective effects on cerebral ischemic, vascular dementia, and Aβ-induced animal models by inhibiting oxidative injury, neuronal apoptosis,(More)
Molecularly imprinted polymeric microspheres with a high recognition ability toward the template molecule, ellagic acid, were synthesized based on distillation-precipitation polymerization. The as-obtained polymers were characterized by scanning electron microscopy, infrared spectroscopy, and thermogravimetric analysis. Static, dynamic, and selective(More)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by amyloid-b (Ab) deposition and neurofibrillary tangles. Dl-PHPB [potassium 2-(1-hydroxypentyl)-benzoate], has been shown to have neuroprotective effects on cerebral ischemic, vascular dementia, and Ab-induced animal models by inhibiting oxidative injury, neuronal apoptosis,(More)
This paper provides a fast and precise tuning method based on linear least-square theory to tune the standard general macro cell propagation model. This method depends on existed tuning methods and the CW (Continuous Wave) testing data of a certain city. Furthermore, using this method can obtain actual outdoor propagation model fitting for TD-SCDMA network.(More)