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Receptor-selective IL-4 mutein modulates inflammatory vascular cell phenotypes and attenuates atherogenesis in apolipoprotein E-knockout mice.
TLDR
The data suggest that IL-4 signaling plays a pivotal role in the regulation of vascular cell phenotypes, and atherogenesis, and theIL-4RI-selective mutein IL- 4/Q116E may have therapeutic potential in vascular diseases.
Vascular smooth muscle cells isolated from adipose triglyceride lipase-deficient mice exhibit distinct phenotype and phenotypic plasticity.
TLDR
The data suggest that ATGL(-/-)mSMC have a distinct phenotype that may be related to vascular pathogenesis and plasticity of SMC phenotypes correlated to lipid metabolism could be a therapeutic target.
Value of EZSCAN parameters for diabetes screening in Chinese.
TLDR
As EZSCAN-diabetes risk score increases, the risk of diabetes increases, and EzSCAN can be used as a tool for screening for diabetes at the best screening diabetes cut-off point value 44.5%, the sensitivity is higher than traditional method of FPG and HbA1c.
Discussion of EZSCAN parameters for diabetes screening in Chinese
TLDR
EZSCAN can be used as a tool for screening for diabetes at the best screening diabetes cut-off point value 44.5%, the sensitivity is higher than traditional method of FPG and HbA 1c, and the risk of diabetes increases.
Receptor-selective interleukin-4 mutein attenuates laser-induced choroidal neovascularization through the regulation of macrophage polarization in mice
TLDR
The results indicated that Dll4 signaling served an important role in the regulation of macrophage polarization, and Employing AdIL-4/Q116E, a IL-4RI-selective mutein, may serve as a new strategy for CNV therapy.
Discussion of EZSCAN Parameters for Diabetes Screening in Chinese
TLDR
EZSCAN can be used as a tool for screening for diabetes at the best screening diabetes cut-off point value 44.5%, the sensitivity is higher than traditional method of FPG and HbA1c, and the sensitivity of EZSCan-diabetes risk score increases, the risk of diabetes increases.
Application of quality evaluation indicators of health checkup based on a three-dimensional quality structure mode
TLDR
This review introduced the application of three-dimensional quality structure pattern in a quality evaluation system of health examination and examined its relationship with the quality evaluation index system based on literature analysis.