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Receptor-selective IL-4 mutein modulates inflammatory vascular cell phenotypes and attenuates atherogenesis in apolipoprotein E-knockout mice.
- Yanhui Lin, Zhiheng Chen, S. Kato
- Biology, MedicineExperimental and molecular pathology
- 1 August 2015
The data suggest that IL-4 signaling plays a pivotal role in the regulation of vascular cell phenotypes, and atherogenesis, and theIL-4RI-selective mutein IL- 4/Q116E may have therapeutic potential in vascular diseases.
Vascular smooth muscle cells isolated from adipose triglyceride lipase-deficient mice exhibit distinct phenotype and phenotypic plasticity.
- Yanhui Lin, S. Chiba, +7 authors S. Kato
- Biology, MedicineBiochemical and biophysical research…
- 10 May 2013
The data suggest that ATGL(-/-)mSMC have a distinct phenotype that may be related to vascular pathogenesis and plasticity of SMC phenotypes correlated to lipid metabolism could be a therapeutic target.
Value of EZSCAN parameters for diabetes screening in Chinese.
As EZSCAN-diabetes risk score increases, the risk of diabetes increases, and EzSCAN can be used as a tool for screening for diabetes at the best screening diabetes cut-off point value 44.5%, the sensitivity is higher than traditional method of FPG and HbA1c.
Discussion of EZSCAN parameters for diabetes screening in Chinese
EZSCAN can be used as a tool for screening for diabetes at the best screening diabetes cut-off point value 44.5%, the sensitivity is higher than traditional method of FPG and HbA 1c, and the risk of diabetes increases.
Receptor-selective interleukin-4 mutein attenuates laser-induced choroidal neovascularization through the regulation of macrophage polarization in mice
- Limo Gao, Wenmin Jiang, Haiying Liu, Zhiheng Chen, Yanhui Lin
- MedicineExperimental and therapeutic medicine
- 27 September 2021
The results indicated that Dll4 signaling served an important role in the regulation of macrophage polarization, and Employing AdIL-4/Q116E, a IL-4RI-selective mutein, may serve as a new strategy for CNV therapy.
Discussion of EZSCAN Parameters for Diabetes Screening in Chinese
EZSCAN can be used as a tool for screening for diabetes at the best screening diabetes cut-off point value 44.5%, the sensitivity is higher than traditional method of FPG and HbA1c, and the sensitivity of EZSCan-diabetes risk score increases, the risk of diabetes increases.
[原著]Type II interleukin-4 receptor-mediated anti-inflammatory response in Mm1 and J774.1 macrophages
Application of quality evaluation indicators of health checkup based on a three-dimensional quality structure mode
This review introduced the application of three-dimensional quality structure pattern in a quality evaluation system of health examination and examined its relationship with the quality evaluation index system based on literature analysis.