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Limited population-based cancer registry data available in China until now has hampered efforts to inform cancer control policy. Following extensive efforts to improve the systematic cancer surveillance in this country, we report on the largest pooled analysis of cancer survival data in China to date. Of 21 population-based cancer registries, data from 17(More)
—Unlike traditional wireless routing protocols which use a single fixed path, opportunistic routing explicitly takes advantage of the broadcast nature of wireless communications by using a set of forwarders to opportunistically perform packet forwarding. A key issue in the design of opportunistic routing protocols is the forwarder list selection problem. In(More)
Formins have long been known to regulate microfilaments but have also recently been shown to associate with microtubules. In this study, Arabidopsis thaliana FORMIN14 (AFH14), a type II formin, was found to regulate both microtubule and microfilament arrays. AFH14 expressed in BY-2 cells was shown to decorate preprophase bands, spindles, and phragmoplasts(More)
Human induced pluripotent stem cells (iPSCs) have been generated with varied efficiencies from multiple tissues. Yet, acquiring donor cells is, in most instances, an invasive procedure that requires laborious isolation. Here we present a detailed protocol for generating human iPSCs from exfoliated renal epithelial cells present in urine. This method is(More)
Mesenchymal stem cells (MSCs) are multipotent cells that have the potential to differentiate into the neuronal cell lineage. Here, we describe the highly efficient and specific induction of cells with neuronal characteristics, without glial differentiation, from human bone marrow-derived mesenchymal stem cells by NRSF silencing. Cells that have the(More)
Providing location recommendations becomes an important feature for location-based social networks (LBSNs), since it helps users explore new places and makes LBSNs more prevalent to users. In LBSNs, <i>geographical influence</i> and <i>social influence</i> have been intensively used in location recommendations based on the facts that geographical proximity(More)
In this paper we extend and generalize the standard random walk theory (or spectral graph theory) on undirected graphs to digraphs. In particular, we introduce and define a (normalized) digraph Laplacian matrix, and prove that 1) its Moore-Penrose pseudo-inverse is the (discrete) Green's function of the di-graph Laplacian matrix (as an operator on(More)
During the past 2 years, an atypical clinical outbreak, caused by a highly pathogenic porcine reproductive and respiratory syndrome virus (PRRSV) with a unique 30-amino-acid deletion in its Nsp2-coding region, was pandemic in China. In this study, we generated four full-length infectious cDNA clones: a clone of the highly virulent PRRSV strain JXwn06(More)
Programmed -1 ribosomal frameshifting (-1 PRF) is a gene-expression mechanism used to express many viral and some cellular genes. In contrast, efficient natural utilization of -2 PRF has not been demonstrated previously in eukaryotic systems. Like all nidoviruses, members of the Arteriviridae (a family of positive-stranded RNA viruses) express their(More)
Forced expression of selected transcription factors can transform somatic cells into embryonic stem cell (ESC)-like cells, termed induced pluripotent stem cells (iPSCs). There is no consensus regarding the preferred tissue from which to harvest donor cells for reprogramming into iPSCs, and some donor cell types may be more prone than others to accumulation(More)