Spatial Epitope Prediction server for Protein Antigens (SEPPA) has received lots of feedback since being published in 2009. In this improved version, relative ASA preference of unit patch and consolidated amino acid index were added as further classification parameters in addition to unit-triangle propensity and clustering coefficient which were previously… (More)
BACKGROUND Depression is the most common form of mental disorder in community and health care settings and current treatments are far from satisfactory. Vagus nerve stimulation (VNS) is a Food and Drug Administration approved somatic treatment for treatment-resistant depression. However, the involvement of surgery has limited VNS only to patients who have… (More)
BACKGROUND The amygdala is a key region in emotion processing, and studies have suggested that amygdala-frontal functional connectivity deficits could be modulated by antidepressants in major depressive disorder (MDD). Transcutaneous vagus nerve stimulation (tVNS), a non-invasive, peripheral neuromodulation method at the ear, has shown promising results in… (More)
An all-digital timing recovery loop is employed in optical coherent receivers, which depends on the number-controlled oscillator and the interpolator to complete timing adjustment in an all-digital way instead of the traditional hybrid way using an analog device (a voltage-controlled oscillator) to adjust the sampling frequency. Therefore it avoids… (More)
In order to select the optimal adaptive algorithm for electrical dispersion equalizer in optical coherent receivers at 100Gbps, this paper focuses on the constant modulus algorithm (CMA) and the least mean square (LMS) algorithm and reaches the conclusion that CMA is more feasible according to the comparison from equalization performance, computation… (More)
Transcutaneous vagus nerve stimulation (tVNS), a non-invasive method of brain stimulation through the auricular branch of the vagus nerve, has shown promising results in treating major depressive disorder (MDD) in several pilot studies. However, the neural mechanism by which the effect on depression might be achieved has not been fully investigated, with… (More)
Deqi sensation, a psychophysical response characterized by a spectrum of different needling sensations, is essential for Chinese acupuncture clinical efficacy. Previous research works have investigated the component of Deqi response upon acupuncture on acupoints on the trunk and limbs. However, the characteristics of Deqi sensations of transcutaneous… (More)
We have examined intra-channel nonlinearity induced distortions in DCF-free coherent transmission system for different modulation formats in detail. Both similarity and dissimilarity of the noise characteristics have been observed and can be explained by the proposed new nonlinear model.
We investigate the ultra-high-speed optical communication system at 400Gb/s per channel based on coherent optical orthogonal frequency division multiplexing (CO-OFDM) through theoretical analysis and simulation, focusing on the required OSNR for 1e-3 BER and system performance under different distortion conditions.
We provide a whole scheme design of the DSP part for POLMUX-NRZ-DQPSK coherent receiver, in which the adoptive algorithm of each module and preferred parameter value of algorithm are discussed. Finally, we demonstrate 8×112Gbit/s DWDM transmissions with a 50GHz channel-spacing over 2000km of SSMF by using the digital coherent receiver.