Yangmei Li

Sort by:

Strain imaging and elasticity reconstruction of arteries based on intravascular ultrasound video images

Mingxi Wan, Yangmei Li, Junbo Li, Yaoyao Cui, Xiaodong Zhou
IEEE Transactions on Biomedical Engineering
2001

Based on intravascular ultrasound (IVUS) video images, a novel motion estimation method combining the genetic algorithm-based optical flow method and a step-by-step and sum strategy has been… (More)

Modeling of peptides containing D-amino acids: implications on cyclization

Austin B. Yongye, Yangmei Li, Marc A. Giulianotti, Yongping Yu, Richard A. Houghten, Karina Martínez-Mayorga
Journal of Computer-Aided Molecular Design
2009

Cyclic peptides are therapeutically attractive due to their high bioavailability, potential selectivity, and scaffold novelty. Furthermore, the presence of D-residues induces conformational… (More)

Macrolactonization of peptide thioesters catalyzed by imidazole and its application in the synthesis of kahalalide B and analogues.

Yangmei Li, Marc Giulionatti, Richard A. Houghten
Organic letters
2010

The macrolactonization of peptide thioester to yield cyclic depsipeptides was developed using imidazole as a catalyst. This strategy was applied to the synthesis of kahalalide B and its analogues.

Fluorescent mu selective opioid ligands from a mixture based cyclic peptide library.

Yangmei Li, Colette T Dooley, +5 authors Richard A. Houghten
ACS combinatorial science
2012

A positional scanning cyclic peptide library was generated using a penta-peptide thioester scaffold. Glycine was fixed at position R(1). Diaminopropionic acid was fixed at position R(3), with its… (More)

High Throughput Synthesis of 2,3,6-Trisubstituted-5,6-Dihydroimidazo[2,1-b]thiazole Derivatives.

Yangmei Li, Marc A. Giulianotti, Richard A. Houghten
Tetrahedron letters
2011

A facile approach to the synthesis of 2,3,6-trisubstituted-5,6-dihydroimidazo[2,1-b]thiazole was reported. A resin bound cyclic thiourea was formed by the treatment of a resin bound diamine with… (More)

Identification of 5,6-dihydroimidazo[2,1-b]thiazoles as a new class of antimicrobial agents.

Yangmei Li, Nina Bionda, +4 authors Lindsey N Shaw
Bioorganic & medicinal chemistry
2016

In an effort to develop novel antimicrobial agents against drug-resistant bacterial infections, 5,6-dihydroimidazo[2,1-b]thiazole compounds were synthesized and tested for their antimicrobial… (More)

The role of imidazole in peptide cyclization by transesterification: parallels to the catalytic triads of serine proteases.

Kendall G. Byler, Yangmei Li, Richard A. Houghten, Karina Martínez-Mayorga
Organic & biomolecular chemistry
2013

The improved bioavailability, stability and selectivity of cyclic peptides over their linear counterparts make them attractive structures in the design and discovery of novel therapeutics. In our… (More)

A Facile Approach to the Synthesis of 3,4-Disubstituted-2-Aminothiazolium Derivatives through the Use of A "Volatilizable" Support.

Yangmei Li, Marc A. Giulianotti, Richard A. Houghten
Tetrahedron letters
2010

A facile solid-phase synthetic approach to the synthesis of 3,4-disubstituted-2-aminothiazolium derivatives was reported. Functionalized aminomethylphenyl silica gel was used as a "volatilizable"… (More)

Synthesis of cyclic peptides through direct aminolysis of peptide thioesters catalyzed by imidazole in aqueous organic solutions.

Yangmei Li, Austin B. Yongye, Marc A. Giulianotti, Karina Martínez-Mayorga, Yongping Yu, Richard A. Houghten
Journal of combinatorial chemistry
2009

A promising method for the synthesis of cyclic peptides through the direct aminolysis of peptide thioesters is presented. The cyclization step was carried out in a mixture of acetonitrile and 1.5 M… (More)

High throughput synthesis of peptide alpha-thioesters through the use of "volatilizable" support.

Yangmei Li, Yongping Yu, Marc A. Giulianotti, Richard A. Houghten
Journal of combinatorial chemistry
2008

Filter Results:

Publication Year

Publication Type

Co-author

Journals and Conferences