Yang Zhan

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Microglia are phagocytic cells that infiltrate the brain during development and have a role in the elimination of synapses during brain maturation. Changes in microglial morphology and gene expression have been associated with neurodevelopmental disorders. However, it remains unknown whether these changes are a primary cause or a secondary consequence of(More)
The B ε-tree File System, or BetrFS, (pronounced " better eff ess ") is the first in-kernel file system to use a write-optimized index. Write optimized indexes (WOIs) are promising building blocks for storage systems because of their potential to implement both microwrites and large scans efficiently. Previous work on WOI-based file systems has shown(More)
Applications frequently request file system operations that traverse the file system directory tree, such as opening a file or reading a file's metadata. As a result, caching file system directory structure and metadata in memory is an important performance optimization for an OS kernel. This paper identifies several design principles that can(More)
Various time-frequency methods have been used to study time-varying properties of non-stationary neurophysiological signals. In the present study, a time-frequency coherence estimate using continuous wavelet transform (CWT) together with its confidence intervals are proposed to evaluate the correlation between two non-stationary processes. The approach is(More)
Upregulation of constitutively-active androgen receptor splice variants (AR-Vs) has been implicated in AR-driven tumor progression in castration-resistant prostate cancer. To date, functional studies of AR-Vs have been focused mainly on their ability to regulate gene expression independent of the full-length AR (AR-FL). Here, we showed that AR-V7 and(More)
A B ε-tree is an example of a write-optimized data structure and can be used to organize on-disk storage for an application such as a database or file system. A B ε-tree provides a key-value API, similar to a B-tree, but with better performance, particularly for inserts, range queries, and key-value updates. This article describes the B ε-tree, compares its(More)
There is considerable interest in the role of coupling between theta and gamma oscillations in the brain in the context of learning and memory. Here we have used a neural network model which is capable of producing coupling of theta phase to gamma amplitude firstly to explore its ability to reproduce reported learning changes and secondly to memory-span and(More)
BACKGROUND How oscillatory brain rhythms alone, or in combination, influence cortical information processing to support learning has yet to be fully established. Local field potential and multi-unit neuronal activity recordings were made from 64-electrode arrays in the inferotemporal cortex of conscious sheep during and after visual discrimination learning(More)
The <b><i>B<sup>&epsiv;</sup>-tree File System</i></b>, or B<i>e</i>trFS (pronounced &#8220;better eff ess&#8221;), is the first in-kernel file system to use a write-optimized data structure (WODS). WODS are promising building blocks for storage systems because they support both microwrites and large scans efficiently. Previous WODS-based file systems have(More)