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Although genome-wide association studies have identified many risk loci associated with colorectal cancer, the molecular basis of these associations are still unclear. We aimed to infer biological insights and highlight candidate genes of interest within GWAS risk loci. We used an in silico pipeline based on functional annotation, quantitative trait loci(More)
Single nucleotide polymorphisms (SNPs) are the most abundant DNA markers in plant genomes. In this study, based on 54,465 SNPs between the genomes of two Indica varieties, Minghui 63 (MH63) and Zhenshan 97 (ZS97) and additional 20,705 SNPs between the MH63 and Nipponbare genomes, we identified and confirmed 1,633 well-distributed SNPs by PCR and Sanger(More)
Extracting emotions from images has attracted much interest , in particular with the rapid development of social networks. The emotional impact is very important for understanding the intrinsic meanings of images. Despite many studies having been done, most existing methods focus on image content, but ignore the emotion of the user who published the image.(More)
Demographics are widely used in marketing to characterize different types of customers. However, in practice, demographic information such as age, gender, and location is usually unavailable due to privacy and other reasons. In this paper, we aim to harness the power of big data to automatically infer users' demographics based on their daily mobile(More)
Granule cell migration influences the laminar structure of the cerebellum and thereby affects cerebellum function. Bergmann glia are derived from radial glial cells and aid in granule cell radial migration by providing a scaffold for migration and by mediating interactions between Bergmann glia and granule cells. In this review, we summarize Bergmann glia(More)
INTRODUCTION Vestibular illusions are the most common illusions that can cause spatial disorientation in flight. This study aims to find out whether and how the ability of keeping arm-hand posture is affected by the vestibular illusions induced by galvanic vestibular stimulation (GVS). METHODS With their heads and trunks firmly fixed, 16 subjects(More)
Liver X receptors (LXRs) are nuclear receptors involved in the regulation of lipid metabolism and inflammatory responses in the central nervous system. Defects in cholesterol homeostasis contribute to the pathogenesis of neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and Huntington’s disease. Inflammatory(More)
This detailed, up-to-date introduction to heterogeneous cellular networking presents its characteristic features, the technology underpinning it, and the issues surrounding its use. Comprehensive and in-depth coverage of core topics catalog the most advanced, innovative technologies used in designing and deploying heterogenous cellular networks, including(More)
We determined the presence of aquaporin-4 (AQP4) antibodies by indirect immunofluorescence in human AQP4-transfected cells, and evaluated the diagnostic and prognostic relevance of AQP4 antibodies in 210 Chinese patients with neuromyelitis optica (NMO), high-risk NMO (HR-NMO), classic multiple sclerosis (MS), and other neurologic diseases. Patients were(More)
Wnt inhibitor factor-1 (WIF-1) is an extracellular antagonist of Wnts secreted proteins. Here we describe the expression pattern of Wif1 throughout the development of the mouse central nervous system (CNS). Wif1 mRNA can be detected as early as the developmental stage E11, and expression persists to adulthood. In embryonic stages, the level of Wif1(More)