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Evolution, substrate specificity and subfamily classification of glycoside hydrolase family 5 (GH5)
- H. Aspeborg, P. Coutinho, Yang Wang, H. Brumer, B. Henrissat
- Biology, Medicine
- BMC Evolutionary Biology
- 20 September 2012
BackgroundThe large Glycoside Hydrolase family 5 (GH5) groups together a wide range of enzymes acting on β-linked oligo- and polysaccharides, and glycoconjugates from a large spectrum of organisms.… Expand
Involvement of genes required for synaptic function in aging control in C. elegans
ObjectiveTo identify new genes required for neurosecretory control of aging in C. elegans.MethodsIn view of the importance of nervous system in aging regulation, we performed the screen for genes… Expand
Pathological consequences of intermittent hypoxia in the central nervous system.
Intermittent hypoxia (IH) is a frequent occurrence in clinical settings. In the last decades, evidence has emerged implicating the gas exchange alterations and sleep disruption associated with those… Expand
Circulating Levels of sFlt1 Splice Variants as Predictive Markers for the Development of Preeclampsia
- Colby A. Souders, S. Maynard, +7 authors T. M. Moore Simas
- Biology, Medicine
- International journal of molecular sciences
- 1 June 2015
Angiogenic biomarkers, including soluble fms-like tyrosine kinase 1 (sFlt1), are thought to be predictors of preeclampsia onset; however, improvement is needed before a widespread diagnostic test can… Expand
Screening for genetic loci affecting the active zone formation in C. elegans.
Objective To screen and identify genetic loci affecting the active zone formation in C. elegans. Methods A SYD-2::GFP reporter was constructed and used as an active zone marker for forward genetic… Expand
Enzymatic characterization of a glycoside hydrolase family 5 subfamily 7 (GH5_7) mannanase from Arabidopsis thaliana
Abstract Each plant genome contains a repertoire of β-mannanase genes belonging to glycoside hydrolase family 5 subfamily 7 (GH5_7), putatively involved in the degradation and modification of various… Expand
Metabonomics Study on the Hepatoprotective Effect of Panax notoginseng Leaf Saponins Using UPLC/Q-TOF-MS Analysis.
- Fang Liu, M. Wang, +6 authors Chenggang Huang
- The American journal of Chinese medicine
- 23 May 2019
Alcohol liver disease is a major public health problem associated with lifestyle. Our recent study demonstrated that the roots of Panax notoginseng saponins (PNS) exert hepatoprotective effects… Expand
Phylogeny and Animal Models
Adults and children frequently suffer from acute or chronic sleep disorders. The presence of one (or more) of these sleep pathologies will usually interfere with normal life, and can result in… Expand
Characterization of an Arabidopsis cadmium-resistant mutant cdr3-1D reveals a link between heavy metal resistance as well as seed development and flowering
A lot of studies have identified many key genes involved in heavy metal detoxification and tolerance in plants; however, our understanding of its molecular mechanisms is far from complete. To gain… Expand
OPRM1 rs1799971 - COMT rs4680 - FAAH rs324420 genes interact with placebo procedures to induce hypoalgesia.
Genetics studies on the placebo hypoalgesic effect highlight a promising link between single nucleotide polymorphisms (SNPs) in the dopamine, opioid, and endocannabinoid genes and placebo… Expand