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Ferulic acid-induced anti-depression and prokinetics similar to Chaihu–Shugan–San via polypharmacology
Meta-analysis of the clinical effectiveness of traditional Chinese medicine formula Chaihu-Shugan-San in depression.
Pharmacokinetic comparisons of albiflorin and paeoniflorin after oral administration of Shaoyao-Gancao-Tang and single herb Paeony decoction to rats.
Results indicated that some components in the other ingredient herb of SGT (Radix Glycyrrhizae) had a pharmacokinetic interaction with albiflor in and paeoniflorin and hence reduced their systematic exposure level.
Meranzin Hydrate Induces Similar Effect to Fructus Aurantii on Intestinal Motility through Activation of H1 Histamine Receptors
Meranzin hydrate can induce similar effect to Fructus Aurantii on intestinal motility and it was, at least in part, mediated by stimulation of H1 histamine receptors.
A potential tool for diagnosis of male infertility: Plasma metabolomics based on GC-MS.
Comparison between the pharmacokinetics of meranzin hydrate in a rat model of chronic depression and in controls following the oral administration of Chaihu-Shugan-San
The pharmacokinetic parameters showed that CMS accelerated the absorption of MH in rats following the oral administration of CSS, indicating that meranzin hydrate may be beneficial in depressive disorders.
Antidepressant-like effects of Chaihu-Shugan-San via SAPK/JNK signal transduction in rat models of depression
CHSGS could obviously improve the depressive state of the model rats and its mechanism may be correlated with regulating the expressions of JNK in the hippocampus.
Enhanced antitumoral efficacy and immune response following conditionally replicative adenovirus containing constitutive HSF1 delivery to rodent tumors
BackgroundOncolytic adenoviruses are promising as anticancer agents but have limited clinical responses. Our previous study showed that heat shock transcription factor 1 (HSF1) overexpression could…
Pretreatment of Shaoyao Gancao Decoction (芍药甘草汤) alters pharmacokinetics of intravenous paclitaxel in rats
SGD administration for 14 consecutive days increased the metabolism of paclitaxel, while a 1-day pretreatment had little effect and would contribute important information to the study on interaction between Chinese medicines and chemotherapy and also help to utilize SGD better in the adjunctive therapy of cancer patients.
A strategy for detecting absorbed bioactive compounds for quality control in the water extract of rhubarb by ultra performance liquid chromatography with photodiode array detector
Physcion was the main active compound of rhubarb against craniocerebral injury via antioxidant pathway and suggested the possibility of a novel quality control of WER in treating TBI injury.