• Publications
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A graph-theoretic modeling on GO space for biological interpretation of gene clusters
MOTIVATION With the advent of DNA microarray technologies, the parallel quantification of genome-wide transcriptions has been a great opportunity to systematically understand the complicatedExpand
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Genetic influence on bone mineral density in Korean twins and families: the healthy twin study
SummaryBone mineral density (BMD), a representative marker of osteoporosis risk, is found to be highly heritable in this Korean study, which is very consistent with the findings in WesternExpand
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Attenuation of telomerase activity by hammerhead ribozyme targeting human telomerase RNA induces growth retardation and apoptosis in human breast tumor cells
Ribozyme possesses specific endoribonuclease activity and catalyzes the hydrolysis of specific phosphodiester bonds, which results in the cleavage of target RNA sequences. Here, we evaluated theExpand
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Constituents of Asarum sieboldii with Inhibitory Activity on Lipopolysaccharide (LPS)‐Induced NO Production in BV‐2 Microglial Cells
Bioassay‐guided fractionation of the root extract of Asarum sieboldii led to the isolation of the four active compounds (−)‐sesamin (1), (2E,4E,8Z,10E)‐N‐(2‐methylpropyl)dodeca‐2,4,8,10‐tetraenamideExpand
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Systematic analysis of cDNA microarray-based CGH.
cDNA microarray-based CGH (Microarray-CGH) is a useful technique for detecting genomic aberrations with a high resolution. However, the criteria for determining a genomic alteration have not beenExpand
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Analysis of differentially expressed genes in early- and late-stage APPsw-transgenic and normal mice using cDNA microarray.
  • S. W. Jee, J. Cho, +9 authors Y. Kim
  • Medicine, Biology
  • International journal of molecular medicine
  • 1 March 2007
The complexity of Alzheimer's disease (AD) has made it difficult to examine its underlying mechanism. A gene microarray offers a solution to the complexity through a parallel analysis of most of theExpand
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Selenocysteine tRNA[Ser]Sec gene is ubiquitous within the animal kingdom.
Recently, a mammalian tRNA which was previously designated as an opal suppressor seryl-tRNA and phosphoseryl-tRNA was shown to be a selenocysteyl-tRNA (B. J. Lee, P. J. Worland, J. N. Davis, T. C.Expand
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Oligonucleotide-based Analysis of Differentially Expressed Genes in Hippocampus of Transgenic Mice Expressing NSE-controlled APPsw
The complexity of Alzheimer’s disease (AD) has made it difficult to examine its underlying mechanisms. A gene microarray offers a solution to the complexity through parallel analysis of most of theExpand
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TOXPO: TOXicogenomics knowledgebase for inferring toxicity based on POlymorphism
Recently, many state-of-the-art omics technologies are being applied to systems toxicology research because evaluation of toxicity in pre-clinical trials is a big issue in the pharmaceuticalExpand
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GOODIES: GO Based Data Mining Tool for Characteristic Attribute Interpretation on a Group of Biological Entities
Issuer Delisting; Order Granting the Application of The Washtenaw Group, Inc. to Withdraw its Common Stock, $.01 par value, from Listing and Registration on the American Stock Exchange LLC File No.Expand
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