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Although the specific mechanism of neuronal damage in human immunodeficiency virus (HIV) -associated dementia is not known, a prominent role for NMDA receptor (NMDAR)-induced excitotoxicity has been demonstrated in neurons exposed to HIV-infected/activated macrophages. We hypothesized NMDAR-mediated activation of the calcium-dependent protease, calpain,(More)
As embedded systems continue to evolve, Java becomes an attractive alternative to traditional languages for embedded hardware platforms. However, there are a number of obstacles for Java to hurdle in order to fulfill all the requirements of any real-time embedded systems. This paper presents an architectural view of a memory design for the embedded Java(More)
The non-adiabatic loss of ERCCL is independent of the size of the associated circuit and the load capacitance; it depends only on the gate count in the circuit. ERCCL does not implement logic through a switch logic network but through capacitance coupling, which decrease its turn-on resistance and adiabatic loss. ERCCL not only reduces dissipation at the(More)
A network is considered observable if its current state can be determined in finite time from knowledge of the observed states. The observability transitions in networks based on random or degree-correlated sensor placement have recently been studied. However, these placement strategies are predominantly based on local information regarding the network. In(More)
Sparsifying transform is an important prerequisite in compressed sensing. And it is practically significant to research the fast and efficient signal sparse representation methods. In this paper, we propose an adaptive K-BRP (AK-BRP) dictionary learning algorithm. The bilateral random projection (BRP), a method of low rank approximation, is used to update(More)
A strain of transmissible gastroenteritis virus (TGEV), SHXB, was isolated in Shanghai, China. The complete genome of strain SHXB was sequenced, and its sequence was compared those of other TGEV strains in the GenBank database. The comparison showed that there were no insertions or deletions in the 5′ and 3′- non-translated regions, in the nonstructural(More)
At microarchitectural level this paper presents our research on performance-constraint problems for VLSI system design with IP and VC cores. With 32bit embedded and low-power processor THUMP105 as an example, delay complexity measure of control module, and signal noise ratio (SNR) of special managing request (SMR) signals were discussed to evaluate final(More)
Amino-noscapine is a promising noscapine derivative undergoing R&D as an efficient anti-tumor drug. In vitro phase I metabolism incubation system was employed. In vitro samples were analyzed using ultra-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry. In vitro recombinant CYP isoforms(More)
Previous reports have demonstrated that the second-generation tetracycline derivative doxycycline (DOX) interrupts mitochondrial proteostasis and physiology, inhibits proliferation of many cell types, and induces apoptosis. However, the effects of DOX, which is widely used in porcine husbandry by feed, on the porcine intestinal epithelium are unclear. In(More)
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