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Although the specific mechanism of neuronal damage in human immunodeficiency virus (HIV) -associated dementia is not known, a prominent role for NMDA receptor (NMDAR)-induced excitotoxicity has been demonstrated in neurons exposed to HIV-infected/activated macrophages. We hypothesized NMDAR-mediated activation of the calcium-dependent protease, calpain,(More)
As embedded systems continue to evolve, Java becomes an attractive alternative to traditional languages for embedded hardware platforms. However, there are a number of obstacles for Java to hurdle in order to fulfill all the requirements of any real-time embedded systems. This paper presents an architectural view of a memory design for the embedded Java(More)
Previous reports have demonstrated that the second-generation tetracycline derivative doxycycline (DOX) interrupts mitochondrial proteostasis and physiology, inhibits proliferation of many cell types, and induces apoptosis. However, the effects of DOX, which is widely used in porcine husbandry by feed, on the porcine intestinal epithelium are unclear. In(More)