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Recent development on distributed systems has shown that a variety of fairness constraints (some of which are only recently defined) play vital roles in designing self-stabilizing population protocols. Current practice of system analysis is, however, deficient under fairness. In this work, we present PAT, a toolkit for flexible and efficient system analysis(More)
FDR, initially introduced decades ago, is the de facto analyzer for Communicating Sequential Processes (CSP). Model checking techniques have been evolved rapidly since then. This paper describes PAT, i.e., a process analysis toolkit which complements FDR in several aspects. PAT is designed to analyze event-based compositional system models specified using(More)
BACKGROUND Among the different types of breast cancer, basal-like breast cancer (BLBC) has an extremely poor prognosis due to its high rate of recurrence and metastasis. The present study aimed to investigate the correlation between the expression of Slug, E-cadherin, and vimentin, and the clinicopathological characteristics and prognosis of patients with(More)
CD1d presentation of alpha-galactosyl ceramides to natural killer T cells has been a focal point of the study of regulatory T cells. KRN7000, an alpha-galactosyl ceramide originally generated from structure activity studies of antitumor properties of marine sponge glycolipids, is currently the most commonly used agonist ligand and is used to stain NKT(More)
Model checking is emerging as an effective software verification method. Although it is desirable to have a dedicated model checker for each application domain, implementing one is rather challenging. In this work, we develop an extensible and integrated architecture in PAT3 (PAT version 3.*) to support the development of model checkers for wide range(More)
UNLABELLED The liver bile acids transporter sodium taurocholate cotransporting polypeptide (NTCP) is responsible for the majority of sodium-dependent bile salts uptake by hepatocytes. NTCP also functions as a cellular receptor for viral entry of hepatitis B virus (HBV) and hepatitis D virus (HDV) through a specific interaction between NTCP and the pre-S1(More)
During the last two decades, model checking has emerged as an effective system analysis technique complementary to simulation and testing. Many model checking algorithms and state space reduction techniques have been proposed. Although it is desirable to have dedicated model checkers for every language (or application domain), implementing one with(More)
Epithelial antimicrobial activity may protect the lung against inhaled pathogens. The bactericidal/permeability-increasing protein family has demonstrated antimicrobial activity in vitro. PLUNC (palate, lung, and nasal epithelium associated) is a 25-kDa secreted protein that shares homology with bactericidal/permeability-increasing proteins and is expressed(More)
Epithelial host defense proteins comprise a critical component of the pulmonary innate immune response to infection. The short palate, lung, nasal epithelium clone (PLUNC) 1 (SPLUNC1) protein is a member of the bactericidal/permeability-increasing (BPI) fold-containing (BPIF) protein family, sharing structural similarities with BPI-like proteins. SPLUNC1 is(More)
Hepatitis D virus (HDV) is the smallest virus known to infect human. About 15 million people worldwide are infected by HDV among those 240 million infected by its helper hepatitis B virus (HBV). Viral hepatitis D is considered as one of the most severe forms of human viral hepatitis. No specific antivirals are currently available to treat HDV infection and(More)