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Downregulation of HDPR1 is associated with poor prognosis and affects expression levels of p120‐catenin and β‐catenin in nonsmall cell lung cancer
The function of HDPR1 on regulating p120ctn may play an important role in human lung carcinogenesis and Restoration ofHDPR1 gene may be a new therapeutic target of lung cancer.
Overexpression of SCC‐S2 correlates with lymph node metastasis and poor prognosis in patients with non‐small‐cell lung cancer
Results indicate that SCC‐S2 plays an important role inNSCLC and might be a useful therapeutic target of NSCLC.
Sporadic Hemangioblastoma of the Kidney: a rare renal tumor
One case of sporadic renal hemangioblastoma happened in a 16-year-old Chinese female patient, presenting with hematuria, and low back pain, which was confirmed by negative immunostaining for cytokeratin and positive staining for α-inhibin, S100 and neuron-specific enolase.
The transcription factor DEC1 (BHLHE40/STRA13/SHARP-2) is negatively associated with TNM stage in non-small-cell lung cancer and inhibits the proliferation through cyclin D1 in A549 and BE1 cells
Results indicate that loss of DEC1 may promote tumor progression in NSCLC through upregulation of cyclin D1, and DEC1 might serve as a novel therapeutic target of NSCLc.
P120-Catenin Isoforms 1 and 3 Regulate Proliferation and Cell Cycle of Lung Cancer Cells via β-Catenin and Kaiso Respectively
The results suggest that p120ctn isoforms 1 and 3 up-regulate cyclin D1, and thereby cyclin E, resulting in the promotion of cell proliferation and cell cycle progression in lung cancer cells probably via different protein mediators.
Connexin 43 recruits E-cadherin expression and inhibits the malignant behaviour of lung cancer cells.
- Hong-Tao Xu, Qing-chang Li, E. Wang
- Biology, MedicineFolia histochemica et cytobiologica
- 6 December 2008
Connexin 43 may induce E-cadherin expression and inhibit cell proliferation and progression of lung cancer in human non-small cell lung cancers (NSCLC).
Reduction of p120ctn isoforms 1 and 3 is significantly associated with metastatic progression of human lung cancer
- Yang Liu, Hong-Tao Xu, S. Dai, Q. Wei, Xi-Ming Yuan, E. Wang
- Biology, MedicineAPMIS : acta pathologica, microbiologica, et…
- 1 July 2007
Reductions of isoforms 1 and 3 may play different roles in metastatic progression of human lung cancer and investigate their relationship to clinicopathological factors in lung squamous cell carcinomas and adenocarcinomas.
Low-grade cribriform cystadenocarcinoma of salivary glands: report of two cases and review of the literature
Low-grade cribriform cystadenocarcinoma (LGCCC) is a recently described rare tumor of salivary gland which exhibits clinically indolent behavior and should be distinguished with papillocystic variant of acinic cell carcinoma.
Abnormal expression of p120-catenin, E-cadherin, and small GTPases is significantly associated with malignant phenotype of human lung cancer.
Overexpression of Axin Downregulates TCF-4 and Inhibits the Development of Lung Cancer
Low expression of axin or augmented expression of TCF-4 is associated with the malignant behavior of lung cancers and can inhibit the ability of lung cancer cells to proliferate and invade.