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The authors aimed to evaluate the validity and characteristics of acoustic rhinometic tests by comparing the results with those of computed tomography (CT) of the nasal cavity. Cross-sectional areas along the nasal cavity were measured by acoustic rhinometry (AR) and CT of the nasal cavity in 30 normal subjects. Cross-sectional areas measured by each(More)
BACKGROUND Adenoid cystic carcinoma (ACC) is a unique tumor characterized by frequent and delayed distant metastasis (DM) with uncommon regional lymph node metastasis. OBJECTIVES To evaluate the factors affecting DM of ACC and survival after appearance of DM. DESIGN A retrospective analysis of 94 cases of ACC from 1979 through 2001. SETTING Academic(More)
OBJECTIVES The internet has become an important source of medical information and a great amount of information related to allergic rhinitis (AR) is available on the internet. However, the quality of this information is still a matter of debate. Therefore, this study was conducted to assess the AR-related information on Korean websites. METHODS The key(More)
Through their rapid periodic actions, the cilia of the human respiratory tract play an important role in clearing inhaled noxious particles. An automated method is developed, based on an image-processing technique, to measure and analyse objectively and quantitatively, ciliary beat frequency (CBF). Microscopic ciliary images are transformed into digitised(More)
Primary ciliary dyskinesia is a genetically determined disorder characterized by immotility or poor motility of the cilia in the airways and elsewhere. Certain specific defects in the ciliary axoneme can be found, which are pathognomonic of the syndrome. The defects include missing dynein arms, abnormally short dynein arms, spokes with no central sheath,(More)
RATIONALE Nasal polyposis implies a refractory clinical course in case of chronic rhinosinusitis (CRS). Although hypoxia is believed to be associated with nasal polyposis, little is known about the mechanism underlying polypogenesis. OBJECTIVES To determine if hypoxia drives nasal polyposis by epithelial-to-mesenchymal transition (EMT). METHODS(More)
OBJECTIVES This study was performed to investigate the changes in ciliary beat frequency (CBF) after treatment with Larginine in the human sinus mucosa and to determine the distribution of inducible nitric oxide synthase (iNOS) and endothelial nitric oxide synthase (eNOS) in the healthy sinus mucosa. STUDY DESIGN/METHODS CBF was measured in the sphenoid(More)
OBJECTIVES This study aimed to investigate the cellular pathogenetic mechanism involved in olfactory tissue injury and regeneration. STUDY DESIGN Adult male mice were exposed to 40 ppm SO2 for 2 hours. METHODS The mice were sacrificed immediately, 4 hours, and 1, 3, 5, 7, 10, 14, and 21 days after exposure to SO2. Olfactory neuroepithelium and bulbs(More)
To evaluate the value of contact laser turbinate surgery using a diode laser in the treatment of idiopathic rhinitis. 53 patients were examined before and after surgery. Six months following surgery, nasal obstruction was significantly improved and a significant decrease in nasal airway resistance was noted on active rhinomanometric measurements (P < 0.05).(More)
CONCLUSION In a retrospective study of 239 cases of fungal sinusitis, noninvasive paranasal sinus aspergillosis was most common and successfully treated by endoscopic sinus surgery (ESS) with postoperative sinus irrigation. For the treatment of fungal sinusitis, ESS with or without antifungal agents and control of predisposing factors for secondary cases(More)