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Previous studies have suggested that breast cancer stem cells (BCSCs) mediate metastasis, are resistant to radiation and chemotherapy, and contribute to relapse. Although several BCSC markers have been described, it is unclear whether these markers identify the same or independent BCSCs. Here, we show that BCSCs exist in distinct mesenchymal-like(More)
We propose to detect abnormal events via a sparse reconstruction over the normal bases. Given a collection of normal training examples, e.g., an image sequence or a collection of local spatio-temporal patches, we propose the sparse reconstruction cost (SRC) over the normal dictionary to measure the normalness of the testing sample. By introducing the prior(More)
In this paper, we present a novel algorithm based on flow velocity field estimation to count the number of pedestrians across a detection line or inside a specified region. We regard pedestrians across the line as fluid flow, and design a novel model to estimate the flow velocity field. By integrating over time, the dynamic mosaics are constructed to count(More)
Cholesteryl ester transfer protein (CETP) shuttles various lipids between lipoproteins, resulting in the net transfer of cholesteryl esters from atheroprotective, high-density lipoproteins (HDL) to atherogenic, lower-density species. Inhibition of CETP raises HDL cholesterol and may potentially be used to treat cardiovascular disease. Here we describe the(More)
Video anomaly detection plays a critical role for intelligent video surveillance. We present an abnormal video event detection system that considers both spatial and temporal contexts. To characterize the video, we first perform the spatio-temporal video segmentation and then propose a new region-based descriptor called “Motion Context,” to(More)
The CETP inhibitor, torcetrapib, was prematurely terminated from phase 3 clinical trials due to an increase in cardiovascular and noncardiovascular mortality. Because nearly half of the latter deaths involved patients with infection, we have tested torcetrapib and other CETPIs to see if they interfere with lipopolysaccharide binding protein (LBP) or(More)
This paper presents a fast obstacle detection (OD) system based on stereo vision for Unmanned Ground Vehicle (UGV) navigation in unstructured environment. In order to make the UGV adaptable to more complex terrains, we propose a new estimation method of the Main Ground Disparity (MGD) from the V-disparity images. Then by comparing the disparity of the MGD(More)
8 h) and high steady-state levels of protein accumulation, while the H2 intrabodies had a half-life of 2 h and less protein at steady state. These results suggest that the choice of sFv as an intrabody depends critically on the intracellular sFv protein having an extended half-life and elevated steady-state level. Thus, extended half-life must be considered(More)