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Kindlin-3 Mediates Integrin αLβ2 Outside-in Signaling, and It Interacts with Scaffold Protein Receptor for Activated-C Kinase 1 (RACK1)*
Background: Kindlin-3 is a cytoplasmic protein that binds and modulates the ligand binding property of integrin αLβ2. Results: Kindlin-3 induces integrin αLβ2 clustering, and it interacts with theExpand
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Sandwich-type Au-PEI/DNA/PEI-Dexa nanocomplex for nucleus-targeted gene delivery in vitro and in vivo.
Many synthetic Au-based cationic nanoparticles (AuNPs) for nonviral gene delivery show high efficiency in vitro, but their excessive charge density, harsh reducing conditions, and nontarget deliveryExpand
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FSCB phosphorylation in mouse spermatozoa capacitation.
It is generally accepted that spermatozoa capacitation is associated with protein kinase A-mediated tyrosine phosphorylation. In our previous study, we identified the fibrous sheath CABYR bindingExpand
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The cytosolic protein talin induces an intermediate affinity integrin alphaLbeta2.
The integrin alphaLbeta2 mediates leukocyte adhesion and migration that are required for a functional immune system. It is known that inside-out signaling triggers alphaLbeta2 conformational changes,Expand
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Intercellular adhesion molecule-3 binding of integrin alphaL beta2 requires both extension and opening of the integrin headpiece.
The leukocyte-restricted integrin alpha(L)beta(2) is required in immune processes such as leukocyte adhesion, migration, and immune synapse formation. Activation of alpha(L)beta(2) by conformationalExpand
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HIPK4 is essential for murine spermiogenesis
Mammalian spermiogenesis is a remarkable cellular transformation, during which round spermatids elongate into chromatin-condensed spermatozoa. The signaling pathways that coordinate this process areExpand
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Roles of Te and Mn in the two phases of manganite with nominal composition La0.6Sr0.1TexMnO3
Powder samples with nominal composition La0.6Sr0.1TexMnO3 (x = 0.00, 0.05, 0.10, 0.15, 0.20) were prepared using the sol-gel method with thermal treatment up to 1473 K. On the basis of powder X-rayExpand
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Study of the free energy of the La1−xCaxMnO3 manganites based on the temperature dependence of the crystal cell volume
A study of the free energy of the perovskite manganites was performed by fitting experimental results for the temperature dependence of the crystal cell volume using a detailed semiclassical model ofExpand
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