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Due to their significant value in both economy and ecology, Daphnia had long been employed to investigate in vivo response of cholinesterase (ChE) in anticholinesterase exposures, whereas the type constitution and property of the enzyme remained unclear. A type of ChE was purified from Daphnia magna using a three-step procedure, i.e., Triton X-100(More)
OBJECTIVE To investigate the chemical constituents in the flowers of Punica granatum. METHODS The chemical constituents were separated by silica gel column chromatography and their structures were determined by spectroscopic experiments. RESULTS As a result, twelve compounds were isolated and identified as oleanolic acid (1), ursolic acid (2), palmitic(More)
A series of lamiridosin A derivatives were synthesized through simple procedures. Their antitumor activities were evaluated against EC9706, MGC803, and B16 cell lines in vitro. Several compounds showed potent antitumor activity, especially compound 10, with IC50 value of 2.36 μmol/L against MGC803 cell lines, is more potent than marketed positive drug(More)
OBJECTIVE To investigate the chemical constituents of Melissa officinalis leaves. METHODS The chemical constituents were separated by silica gel column chromatography and their structures were determined by spectroscopic experiments. RESULTS 13 compounds were isolated and identified as protocatechuyl aldehyde(1), serratagenic acid(2), vanillin(3),(More)
OBJECTIVE It has been reported that soluble intercellular adhesion molecule-1 (sICAM-1) participates in many immune and inflammatory reactions. Its expression and role in severe pneumonia has not fully been understood. This study aimed to investigate the changes of sICAM-1 expression in severe pneumonia and the relationship between sICAM-1 and severe(More)
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