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All too often a seemingly insurmountable divide between theory and practice can be witnessed. In this paper we try to contribute to narrowing this gap in the field of ad-hoc routing. In particular we consider two aspects: We propose a new geometric routing algorithm which is outstandingly efficient on <i>practical</i> average-case networks, however is also(More)
As the technology progresses, interconnect delays have become bottlenecks of chip performance. 3D integrated circuits are proposed as one way to address this problem. However, thermal problem is a critical challenge for 3D IC circuit design. We propose a thermal-driven 3D floorplanning algorithm. Our contributions include: (1) a new 3D floorplan(More)
We present a new Euclidean distance for images, which we call image Euclidean distance (IMED). Unlike the traditional Euclidean distance, IMED takes into account the spatial relationships of pixels. Therefore, it is robust to small perturbation of images. We argue that IMED is the only intuitively reasonable Euclidean distance for images. IMED is then(More)
Systemic lupus erythematosus is a complex and potentially fatal autoimmune disease, characterized by autoantibody production and multi-organ damage. By a genome-wide association study (320 patients and 1,500 controls) and subsequent replication altogether involving a total of 3,300 Asian SLE patients from Hong Kong, Mainland China, and Thailand, as well as(More)
Funded by the National Institute of Allergy and Infectious Diseases, the Pathosystems Resource Integration Center (PATRIC) is a genomics-centric relational database and bioinformatics resource designed to assist scientists in infectious-disease research. Specifically, PATRIC provides scientists with (i) a comprehensive bacterial genomics database, (ii) a(More)
Heat dissipation is one of the most serious challenges in 3-D IC designs. One effective way of reducing circuit temperature is to introduce thermal through-the-silicon (TTS) vias. In this paper, we extended the TTS-via planning in a multilevel routing framework by Cong and Zhang (2005), but use a much enhanced TTS-via planning algorithm. We formulate the(More)
The Pathosystems Resource Integration Center (PATRIC) is the all-bacterial Bioinformatics Resource Center (BRC) (http://www.patricbrc.org). A joint effort by two of the original National Institute of Allergy and Infectious Diseases-funded BRCs, PATRIC provides researchers with an online resource that stores and integrates a variety of data types [e.g.(More)
SUMMARY A full-length cDNA encoding a putative diacylglycerol acyltransferase 1 (DGAT1, EC was obtained from Tropaeolum majus (garden nasturtium). The 1557-bp open reading frame of this cDNA, designated TmDGAT1, encodes a protein of 518 amino acids showing high homology to other plant DGAT1s. The TmDGAT1 gene was expressed exclusively in(More)
This paper presents MARS, a novel multilevel full-chip gridless routing system. The multilevel framework with recursive coarsening and refinement allows for scaling of our gridless routing system to very large designs. The downward pass of recursive coarsening builds the representations of routing regions at different levels while the upward pass of(More)
The ongoing neural activity in human primary somatosensory cortex (SI) is characterized by field potential oscillations in the 7-13 Hz range known as the mu rhythm. Recent work has shown that the magnitude of the mu oscillation immediately preceding the onset of a weak stimulus has a significant impact on its detection. The neural mechanisms mediating this(More)