Yan-You Lin

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Picoliter droplets actuated on an electrowetting-on-dielectric (EWD) actuator are demonstrated. In this study, the physical scaling of electrodes for 33 ␮m and 21 ␮m EWD devices resulted in droplets of 12 pl and 5 pl being dispensed respectively in conjunction with 3 ␮m SU8 gaskets. The stacked multi-layer insulators in the actuators consisted of 200 nm(More)
A low voltage, two-level-metal, and multi-layer insulator electrowetting-on-dielectric (EWD) platform is presented. Dispensing 300 pl droplets from 140 nl closed on-chip reservoirs was accomplished with as little as 11.4 V solely through EWD forces, and the actuation threshold voltage was 7.2 V with a 1 Hz voltage switching rate between electrodes. EWD(More)
The results of investigations into performing DNA sequencing chemistry on a picoliter-scale electrowetting digital microfluidic platform are reported. Pyrosequencing utilizes pyrophosphate produced during nucleotide base addition to initiate a process ending with detection through a chemiluminescence reaction using firefly luciferase. The intensity of light(More)
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