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The Target of the NSD Family of Histone Lysine Methyltransferases Depends on the Nature of the Substrate*
The NSD (nuclear receptor SET domain-containing) family of histone lysine methyltransferases is a critical participant in chromatin integrity as evidenced by the number of human diseases associatedExpand
ChIP-seq reveals broad roles of SARD1 and CBP60g in regulating plant immunity
Recognition of pathogens by host plants leads to rapid transcriptional reprogramming and activation of defence responses. The expression of many defence regulators is induced in this process, but theExpand
The toxic effects of microcystin-LR on the reproductive system of male rats in vivo and in vitro.
The aim of this study was to investigate whether microcystin-LR, one of the most common cyanobacterial toxins has toxic effects on reproductive system in vivo or Leydig cells in vitro. Male rats wereExpand
The cytosolic Fe-S cluster assembly component MET18 is required for the full enzymatic activity of ROS1 in active DNA demethylation
DNA methylation patterns in plants are dynamically regulated by DNA methylation and active DNA demethylation in response to both environmental changes and development of plant. Beginning with theExpand
Heavy metals in food crops, soil, and water in the Lihe River Watershed of the Taihu Region and their potential health risks when ingested.
Environmental pollution by heavy metals resulting from rapid economic development is a major concern. Soil, water, wheat, and rice samples were collected from the Lihe River Watershed in the TaihuExpand
The role of C5a in acute lung injury induced by highly pathogenic viral infections
The complement system, an important part of innate immunity, plays a critical role in pathogen clearance. Unregulated complement activation is likely to play a crucial role in the pathogenesis ofExpand
Mitosin/CENP-F as a Negative Regulator of Activating Transcription Factor-4*
Mitosin/CENP-F is a human nuclear matrix protein with multiple leucine zipper motifs. Its accumulation in S-G2 phases and transient kinetochore localization in mitosis suggest a multifunctionalExpand
Microcystin-LR causes cytotoxicity effects in rat testicular Sertoli cells.
  • Yan Li, X. Han
  • Biology, Medicine
  • Environmental toxicology and pharmacology
  • 1 March 2012
Microcystins (MCs) are produced by cyanobacteria. The most toxic and widely distributed MC is microcystin-LR (MC-LR). The aim of this study was to investigate whether exposure to MC-LR could induceExpand
Interleukin-17 (IL-17)-induced MicroRNA 873 (miR-873) Contributes to the Pathogenesis of Experimental Autoimmune Encephalomyelitis by Targeting A20 Ubiquitin-editing Enzyme*
Background: The regulatory mechanism of abnormal miRNA expression in astrocytes upon IL-17 stimulation remains unclear. Results: miR-873 induced by IL-17 promotes inflammatory cytokine production andExpand
Tunable Valley Polarization and Valley Orbital Magnetic Moment Hall Effect in Honeycomb Systems with Broken Inversion Symmetry
In this Letter, a tunable valley polarization is investigated for honeycomb systems with broken inversion symmetry such as transition-metal dichalcogenide MX2 (M = Mo, W; X = S, Se) monolayersExpand