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OBJECTIVE To explore arsenic-induced oxidative stress and the protective efficacy of α-lipoic acid and vitamin c. METHODS 50 male SD rats were randomly divided into 5 groups. Ten rats (the control group) were exposed to deionized water for 6 weeks, and the others were alone exposed to sodium arsenite (50 mg/L water) for 6 weeks, at the same time, three(More)
AIM To study changes of inflammation-associated cytokine expressions during early phase of endotoxic shock in macaque. METHODS Experiments were performed in Macaque mulatta treated with LPS 2.8 mg/kg in shock model group or with normal saline in control group. Blood samples were collected before, or 60 min, or 120 min after LPS injection, respectively.(More)
AIM To evaluate the correlation of shear wave elastography (SWE) results with liver fibrosis histology and quantitative function reserve. METHODS Weekly subcutaneous injection of 60% carbon tetrachloride (1.5 mL/kg) was given to 12 canines for 24 wk to induce experimental liver fibrosis, with olive oil given to 2 control canines. At 24 wk, liver condition(More)
The aim of the present study was to investigate the distribution of CD4 + CD25 + regulatory T cells (Tregs) in the peripheral blood of patients with chronic hepatitis C; in addition to identifying whether the distribution of CD4 + CD25 + Tregs predicts the efficacy of antiviral therapy for HCV. The expression of CD4 + CD25 + forkhead box protein (FOXP) 3 +(More)
OBJECTIVE To explore the expression changes of mRNA and protein of uncoupling protein 2 (UCP2) in adipose tissues and uncoupling protein 3 (UCP3) in muscle tissues of rats which were treated with repeated fasting/refeeding and followed by fed with high-fat diet, and their possible mechanism on lipid metabolism. METHODS The model of repeating(More)
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