• Publications
  • Influence
Towards the Small and the Beautiful: A Small Dibromotyrosine Derivative from Pseudoceratina sp. Sponge Exhibits Potent Apoptotic Effect through Targeting IKK/NFκB Signaling Pathway
TLDR
The results of a set of experiments designed to reveal the underlying mechanism of DT cytotoxic activity against K562 cells suggested that DT can act as a topoisomerase II catalytic inhibitor, unlike the clinical anticancer drug, etoposide, which acts as aTopoisomersase poison.
Effects of Nuclear Power Plant Thermal Effluent on Marine Sessile Invertebrate Communities in Southern Taiwan
The present study aimed at determining the impact of cooling water discharge from a Nuclear Power Plant in Kenting, Taiwan on the recruitment patterns of marine invertebrates. Field experiments were
Immunomodulatory Polyketides from a Phoma-like Fungus Isolated from a Soft Coral.
TLDR
A preliminary structure-activity analysis revealed a crucial role of Δ7 and a terminal OH group in the regulation of CD3+ T cell proliferation and the first report of immunoregulatory activity for metabolites of this kind is reported.
Cytotoxic Sesterterpenoids from a Sponge Hippospongia sp.
TLDR
The structures of these compounds were elucidated on the basis of their spectroscopic data and comparison of the NMR data with those of known analogues.
Osteoclastogenesis Inhibitory Polyketides from the Sponge‐Associated Fungus Xylaria feejeensis
A new ten‐membered macrolide (1) and a new α‐pyrone derivative, (−)‐annularin C (2), together with 14 known analogs (3–16) were isolated from the AcOEt extract of the fungus Xylaria feejeensis
Cytotoxic C21 and C22 terpenoid-derived metabolites from the sponge Ircinia sp.
TLDR
Among these metabolites, 2 is the first C21 terpenoid-derived metabolite to be reported from this genus, and exhibited significant cytotoxic activity against K562, DLD-1, HepG2, and Hep3B cancer cell lines.
Spatial distribution of sponge spicules in sediments around Taiwan and the Sunda Shelf
Biogenic silica (BSi) in marine sediments is an important indicator of siliceous organism distributions and paleoproductivities. Organisms that have BSi skeletons include diatoms, silicoflagellates,
Assessment of Degree of Maturity of Compost Produced by Different Kitchen Waste Composting Methods
Kitchen waste in general has high water content with various plant required nutrients and organic matters but is non-toxic, and therefore, it is a good composting material. Three different composting
Recent progress of molecular cytogenetic study on scleractinian (stony) corals
TLDR
A newly improved method for suitable chromosome preparations made from coral embryos for FISH is devised and significant progress is made in molecular cytogenetic study of stony corals by FISH using the authors' methods for making chromosome preparations.