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In this paper, we extend the relaxed positive-definite and skew-Hermitian splitting preconditioner (RPSS) for generalized saddle-point problems in [J.-L. Zhang, C.-Q. Gu and K. Zhang, Appl. Math. Comput. 249(2014)468-479] by introducing an additional parameter. The spectral properties of the presented new preconditioned matrix for generalized saddle-point(More)
The metanephric mesenchyme (MM) cells are a subset of kidney progenitor cells and play an essential role in mesenchymal-epithelial transition (MET), the key step of nephron generation. Six2, a biological marker related to Wnt signaling pathway, promotes the proliferation, inhibits the apoptosis and maintains the un-differentiation of MM cells. Besides, LiCl(More)
BACKGROUNDS/AIMS Vitamin C is an antioxidant and acts as a cofactor for several key enzymatic catalytic reactions in animals. Amphibians produce vitamin C in their kidneys, as opposed to mammals that produce vitamin C in their liver. Gulo serves as a crucial enzyme for vitamin C synthesis in mammals, but the characteristics and localization of its(More)
Protein tyrosine phosphorylation is an important mechanism that regulates cytoskeleton reorganization and cell spreading of migratory cells. A number of cytoskeletal proteins are known to be tyrosine phosphorylated (pY) in different cellular processes. However, the profile of pY proteins during different stages of cell spreading has not been available.(More)