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Yersinia pestis genome sequencing identifies patterns of global phylogenetic diversity
Plague is a pandemic human invasive disease caused by the bacterial agent Yersinia pestis. We here report a comparison of 17 whole genomes of Y. pestis isolates from global sources. We also screenedExpand
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  • Open Access
A Glimpse of Streptococcal Toxic Shock Syndrome from Comparative Genomics of S. suis 2 Chinese Isolates
Background Streptococcus suis serotype 2 (SS2) is an important zoonotic pathogen, causing more than 200 cases of severe human infection worldwide, with the hallmarks of meningitis, septicemia,Expand
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Historical variations in mutation rate in an epidemic pathogen, Yersinia pestis
  • Y. Cui, C. Yu, +30 authors R. Yang
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences
  • 27 December 2012
The genetic diversity of Yersinia pestis, the etiologic agent of plague, is extremely limited because of its recent origin coupled with a slow clock rate. Here we identified 2,326 SNPs from 133Expand
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  • Open Access
Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans.
Genomics provides an unprecedented opportunity to probe in minute detail into the genomes of the world's most deadly pathogenic bacteria- Yersinia pestis. Here we report the complete genome sequenceExpand
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Genetics of metabolic variations between Yersinia pestis biovars and the proposal of a new biovar, microtus.
Yersinia pestis has been historically divided into three biovars: antiqua, mediaevalis, and orientalis. On the basis of this study, strains from Microtus-related plague foci are proposed toExpand
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Insight into Microevolution of Yersinia pestis by Clustered Regularly Interspaced Short Palindromic Repeats
Background Yersinia pestis, the pathogen of plague, has greatly influenced human history on a global scale. Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR), an element participatingExpand
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Microarray Analysis of Temperature‐Induced Transcriptome of Yersinia pestis
Yersinia pestis, the etiologic agent of plague, must acclimatize itself to temperature shifts between the temperature (26 C) for flea blockage and the body temperature (37 C) of warm‐blooded hostsExpand
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Novel Plasmid and Its Variant Harboring both a blaNDM-1 Gene and Type IV Secretion System in Clinical Isolates of Acinetobacter lwoffii
  • Hongyan Hu, Y. Hu, +14 authors B. Zhu
  • Biology, Medicine
  • Antimicrobial Agents and Chemotherapy
  • 30 January 2012
ABSTRACT The spread of the blaNDM-1 gene is gaining worldwide attentions. This gene is usually carried by large plasmids and has been discovered in diverse bacteria since it was originally found inExpand
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Involvement of the Post-Transcriptional Regulator Hfq in Yersinia pestis Virulence
Background Yersinia pestis is the causative agent of plague, which is transmitted primarily between fleas and mammals and is spread to humans through the bite of an infected flea or contact withExpand
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  • Open Access
Identification of Staphylococcus aureus and determination of its methicillin resistance by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
To evaluate the performance of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) in identifying Staphylococcus aureus and in determining its methicillinExpand
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