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Yersinia pestis genome sequencing identifies patterns of global phylogenetic diversity
TLDR
The phylogenetic analysis suggests that Y. pestis evolved in or near China and spread through multiple radiations to Europe, South America, Africa and Southeast Asia, leading to country-specific lineages that can be traced by lineage-specific SNPs. Expand
A Glimpse of Streptococcal Toxic Shock Syndrome from Comparative Genomics of S. suis 2 Chinese Isolates
TLDR
Light is shed on STSS triggered by SS2 at the genomic level, facilitates further understanding of its pathogenesis and points to directions of development on some effective strategies to combat highly pathogenic SS2 infections. Expand
Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans.
TLDR
It is concluded that strain 91001 and other strains isolated from M. brandti might have evolved from ancestral Y. pestis in a different lineage and may contribute to its unique nonpathogenicity to humans and host-specificity. Expand
Insight into Microevolution of Yersinia pestis by Clustered Regularly Interspaced Short Palindromic Repeats
TLDR
CRISPR can provide important information for genotyping and evolutionary research of bacteria, which will help to trace the source of outbreaks and make possible the development of very low cost and high-resolution assays for the systematic typing of any new isolate. Expand
Microarray Analysis of Temperature‐Induced Transcriptome of Yersinia pestis
TLDR
A whole‐genome DNA microarray was used to investigate transcriptional regulation upon the upshift of growth temperature from 26 to 37 C in a chemically defined medium and strikingly, many gene clusters displayed a co‐transcription pattern in response to temperature upshift. Expand
Involvement of the Post-Transcriptional Regulator Hfq in Yersinia pestis Virulence
TLDR
It appears that Hfq acts by controlling the expression of many virulence- and stress-associated genes, probably in conjunction with small noncoding RNAs, as a key regulator involved in Y. pestis stress resistance, intracellular survival and pathogenesis. Expand
Identification of Staphylococcus aureus and determination of its methicillin resistance by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
TLDR
Comparison of MALDI-TOF MS spectral profiles of microorganism could serve as a simple and rapid method for bacterial identification and antibiotic susceptibility analysis. Expand
Genotyping and Phylogenetic Analysis of Yersinia pestis by MLVA: Insights into the Worldwide Expansion of Central Asia Plague Foci
TLDR
The relationships among the strains in China, Central Asia and the rest of the world based on the MLVA25 assay provide an unprecedented view on the expansion and microevolution of Y. pestis. Expand
The Iron-Responsive Fur Regulon in Yersinia pestis
TLDR
Fur is a global regulator, both an activator and a repressor, and directly controls not only almost all of the iron assimilation functions but also a variety of genes involved in various non-iron functions for governing a complex regulatory cascade in Y. pestis. Expand
Characterization of Zur-dependent genes and direct Zur targets in Yersinia pestis
TLDR
Zur as a repressor directly controls the transcription of znuA, znuCB and ykgM-RpmJ2 in Y. pestis by employing a conserved mechanism of Zur-promoter DNA association as observed in γ-Proteobacteria. Expand
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