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—This paper applies Convolutional Neural Networks (CNNs) for offline handwritten English character recognition. We use a modified LeNet-5 CNN model, with special settings of the number of neurons in each layer and the connecting way between some layers. Outputs of the CNN are set with error-correcting codes, thus the CNN has the ability to reject(More)
To develop a growing root, cell division in the root meristem has to be properly regulated in order to generate or propagate new cells. How cell division is regulated in the root meristem remains largely unknown. Here, we report the identification and characterization of the Arabidopsis (Arabidopsis thaliana) RETARDED ROOT GROWTH (RRG) gene that plays a(More)
Although much recent evidence has demonstrated that neuroinflammation contributes to volatile anesthetic-induced cognitive deficits, there are few existing mechanistic explanations for this inflammatory process. This study was conducted to investigate the effects of the volatile anesthetic isoflurane on canonical nuclear factor (NF)-κB signaling, and to(More)
Melatonin is an endogenous hormone with neuroprotective effects. Melatonin levels in elderly patients are reduced after surgeries that require anaesthesia. Whether reduced melatonin levels are important for postoperative cognitive dysfunction (POCD) remains unclear. Here, we investigated the effects of melatonin on cognitive dysfunctions induced by(More)
  • Zhen Li, Meilian Jin, Yanzong Li, To, Limin Liu, Michael D Zoltowski +34 others
  • 2005
memory of my grandmother, Zhugu Cai. iii ACKNOWLEDGMENTS I would like to thank my advisor, Professor Edward J. Delp, for his guidance and support. I truly appreciate the research freedom he allowed. And I am deeply grateful for his reminder to keep focused when I was zigzagging with various research topics, and his advice to look deeper into one challenging(More)
Angiogenesis is an essential step for the growth and spread of malignant tumors. Accurate detection and quantification of tumor angiogenesis is important for early diagnosis of cancers as well as post therapy assessment of antiangiogenic drugs. The cell adhesion molecule integrin αvβ3 is a specific marker of angiogenesis, which is highly expressed on(More)
The underlying mechanism of isoflurane-induced cognitive dysfunction in older individuals is unknown. In this study, the effects of isoflurane exposure on the hippocampal blood-brain barrier (BBB) in aged rats were investigated because it was previously shown that BBB disruption involves in cognitive dysfunction. Twenty-month-old rats randomly received 1.5%(More)
In layered peer-to-peer streaming, as the bandwidth and data availability (number of layers received) of each peer node are constrained and heterogeneous, the media server can still become overloaded, and the streaming qualities of the receiving nodes may also be constrained for the limited number of supplying peers. This paper identifies these issues and(More)
Endovascular technology was initially applied in treating peripheral vascular disease and was further developed in managing coronary artery disease. During the latest two decades, it has been introduced into the arena of cerebrovascular diseases, which has garnered attention and research interests.