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A 4-wk training program was undertaken by 15 untrained non-heat-acclimated males who were divided into three groups matched on maximal aerobic capacity (VO2max) and trained either in water or on land to determine how physical training (PT) in these different media affects heat tolerance. Subjects trained on a cycle ergometer for 1 h/day, 5 days/wk at 75%(More)
Differences between acclimation to heat at the end of winter (W) and at the end of summer (S) were studied on the same eight male volunteers. Subjects were exposed to 40 degrees C, 30% rh for 10 consecutive days on two separate occasions approximately 5 mo apart (S and W). Daily exposures lasted 120 min: 10 min rest, 50 min walking 1.34 m . s-1 on the(More)
Sixty volunteers, 33 males and 27 females (18-63 yr), were divided according to age and sex. They were exposed for 10 min to extreme dry heat: 80-90 degrees C dry bulb temperature and 3-4% relative humidity. Their rectal temperature, skin temperature at eight different points, weight, and heart rate were recorded prior to and immediately following the(More)
Heat acclimation has been suggested to either lower or have no effect on the rate of metabolism (M) elicited by muscular exercise. The purpose of the present investigation (Study I) was to examine the effect heat acclimation has on the M (W . kg-1 or VO2 in ml . kg-1 . min-1) elicited by muscular exercise. Two additional investigations were evaluated to(More)
Metabolic heat production (M), clothing heat transfer characteristics, and the environment dictate a required evaporative cooling (Ereq) from the body to maintain thermal balance. However, the maximal evaporative capacity (Emax) is dictated by vapor transfer properties of the clothing and environment. Relationships between metabolic load, environmental(More)
Nine young men who had suffered from heatstroke on previous occasions (heat-intolerant subjects) and 10 young volunteers (control subjects) were examined to determine their physiologic responses to exercise in temperate (23 degrees C) and hot environments (40 degrees C). The tests included an orthostatic test, work loads of 40 W and 80 W, and oxygen(More)
Lithium (Li) reduces brain inositol levels. Berridge has suggested that this effect is related to Li's mechanism of action. It had previously been shown that pilocarpine causes a limbic seizure syndrome in lithium treated rats, and that these lithium-pilocarpine seizures are reversible by intracerebroventricular inositol administration to rats. We now show(More)