Yahya Büyükaşık

Learn More
 Plasma concentrations of the most potent megakaryocytopoietic cytokines, thrombopoietin (TPO) and interleukin-6 (IL-6), and the platelet activation marker P-selectin were evaluated in 24 patients with autoimmune thrombocytopenic purpura (ATP) who responded to conventional steroid treatment, at diagnosis and after steroid-induced recovery. Baseline TPO(More)
 Leukemic infiltration of the prostate is unusual. Acute retention of urine as the first clinical manifestation of an unsuspected, asymptomatic chronic lymphocytic leukemia (CLL) is found only in sporadic case reports. This report documents a case of CLL in a 65-year-old man presenting with acute urinary retention. The literature pertinent to this topic is(More)
To the editor, A 74-year-old male patient—who had been followed for B cell chronic lymphocytic leukemia (CLL) for the previous 2 years—presented with swelling and tenderness in the small joints of his hands and feet; pain in his elbow, shoulder and knee joints symmetrically. He declared that he had suffered from his joint complaints for nearly 15 months. In(More)
OBJECTIVE The prominent functions of the local renin-angiotensin system (RAS) in primitive hematopoiesis further support the hypothesis that local autocrine bone marrow RAS could also be active in neoplastic hematopoiesis. The aim of this study is to examine critical RAS elements in normal CD34+ hematopoietic stem cells and multiple myeloma (MM)-related(More)
UNLABELLED Additional chromosomal abnormalities in acute myelogenous leukemia have been identified as one of the most important prognostic factors. Favorable chromosomal changes such as t(8;21), inv(16), and t(15;17) are associated with higher rates of complete remission and event-free survival. Translocation (15;17) characterizes acute promyelocytic(More)
OBJECTIVES Reactive haemophagocytic syndrome (RHS) is a hyperinflammatory disorder often occurring in the background of several disorders such as infections, malignancies, and rheumatic diseases. Recently, a score known as the HScore was developed for the diagnosis of RHS. In the original study, most of the patients had underlying haematological malignancy(More)
Iron studies in chronic liver diseases (CLDs) have a long history. Currently we can mention certainties, uncertainties, and hopes related to this topic. It is certain that iron metabolism problems and hepatic siderosis are frequent in CLDs and they get more frequent as CLD progresses, but true iron overload is rare. There are conflicting literature data on(More)
Thank you very much for your valuable comments and sharing your experience. We agree for your contribution. In thalassemia patients, several transplantation centers categorised risk factors prior to allogenic hematopoietic stem cell transplantation. Pesaro classification assigned patients to three arms according to the absence or presence of one, two or(More)
OBJECTIVE Bleeding disorders are a very important health problem due to the associated high risk of hemorrhage during dental procedures. The present study aimed to investigate oral manifestations of inherited disorders of platelet function (IDPF). METHODS The study included 20 IDPF patients (mean age: 31.90±10.71 years) and 40 healthy controls (mean age:(More)
OBJECTIVE Multiple myeloma (MM) is currently incurable due to refractory disease relapse even under novel anti-myeloma treatment. In silico studies are effective for key decision making during clinicopathological battles against the chronic course of MM. The aim of this present in silico study was to identify individual genes whose expression profiles match(More)