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Arsenic (As) is a neurotoxin induces dysfunction of learning and memory. Research has indicated that cerebellum may be involved in arsenic-induced impairment of learning and memory. However, the molecular mechanisms that underlie these effects remain unclear. This study screened for the differentially expressed genes related to the long-term potentiation(More)
Small molecular drugs that can combine with target proteins specifically, and then block relative signal pathway, finally obtain the purpose of treatment. For this reason, the synthesis of novel imidazole derivatives was described and this study explored the details of imidazole derivatives binding to human serum albumin (HSA). The data of steady-state and(More)
Monoethanolamine (MEA) based liquids are widely used materials for postcombustion CO2 capture. We report here an extensive ab initio molecular dynamic (AIMD) simulation study on CO2 sorption in water-free MEA liquid with a range of CO2 contents at 313 K. The simulation reveals the detailed CO2 capture mechanism that leads to the initial formation of a(More)
Drug repositioning can reduce the time, costs and risks of drug development by identifying new therapeutic effects for known drugs. It is challenging to reposition drugs as pharmacological data is large and complex. Subnetwork identification has already been used to simplify the visualization and interpretation of biological data, but it has not been(More)
Nitrogen-rich porous carbons (NPCs) were synthesized from 1,5-dihydroxynaphthalene, urea, and formaldehyde based on benzoxazine chemistry by a soft-templating method with KOH chemical activation. They possess high surface areas of 856.8-1257.8 m(2) g(-1), a large pore volume of 0.15-0.65 cm(3) g(-1), tunable pore structure, high nitrogen content (5.21-5.32(More)
A hyperbranched conjugated Schiff base polymer network was synthesized by condensation between 4,4',4''-nitrilotribenzaldehyde and p-phenylenediamine. The material exhibits excellent rate capability and long cycle life for lithium storage. Coupled with lower electrode potential (0.7 V vs. Li(+)/Li), it may be well suited for fully flexible thin film(More)
Nitrogen-enriched hierarchically porous carbons (HPCs) were synthesized from a novel nitrile-functionalized benzoxazine based on benzoxazine chemistry using a soft-templating method and a potassium hydroxide (KOH) chemical activation method and used as electrode materials for supercapacitors. The textural and chemical properties could be easily tuned by(More)
Conductive processes involving lithium ions are analyzed in detail from a mechanistic perspective, and demonstrate that single ion polymeric electrolyte (SIPE) membranes can be used in lithium-ion batteries with a wide operating temperature range (25-80 °C) through systematic optimization of electrodes and electrode/electrolyte interfaces, in sharp contrast(More)