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The utility of genome editing technologies for disease modeling and developing cellular therapies has been extensively documented, but the impact of these technologies on mutational load at the whole-genome level remains unclear. We performed whole-genome sequencing to evaluate the mutational load at single-base resolution in individual gene-corrected human(More)
Nowadays wireless sensor network (WSN) is widely used in human-centric applications and environmental monitoring. Different institutes deploy their own WSNs for data collection and processing. It becomes a challenging problem when institutes collaborate to do data mining while intend to keep data privacy on each side. Privacy preserving data mining (PPDM)(More)
Y haplogroup analyses are an important component of genealogical reconstruction, population genetic analyses, medical genetics and forensics. These fields are increasingly moving towards use of low-coverage, high throughput sequencing. However, there is as yet no software available for using sequence data to assign Y haplogroup groups probabilistically,(More)
Y haplogroup analyses are an important component of genealogical reconstruction, population genetic analyses, medical genetics and forensics. These fields are increasingly moving towards use of low-coverage, high throughput sequencing. While there have been methods recently proposed for assignment of Y haplogroups on the basis of high-coverage sequence(More)
There is an increasing trend for data owners to store their data in a third-party cloud server and buy the service from the cloud server to provide information to other users. To ensure confidentiality, the data is usually encrypted. Therefore, an encrypted data searching scheme with privacy preserving is of paramount importance. Predicate encryption (PE)(More)
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