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Gas2l3, a Novel Constriction Site-Associated Protein Whose Regulation Is Mediated by the APC/CCdh1 Complex
TLDR
Overexpression of Gas2l3 specifically interferes with cell abscission, which is the final stage of cell division, when the cutting of the intercellular bridge at the constriction sites occurs, and is suggested to be part of the cellular mechanism that terminates cell division. Expand
Gas2l3 is essential for brain morphogenesis and development.
TLDR
This study provides the first insight into the function of gas2l3 in vivo, demonstrating its essential role in brain development and loss-of-function experiments. Expand
Gas 2 l 3 , a Novel Constriction Site-Associated Protein Whose Regulation Is Mediated by the \ ( APC / C ^ { Cdh 1 } \ ) Complex
Growth arrest-specific 2-like protein 3 (Gas2l3) was recently identified as an Actin/Tubulin cross-linker protein that regulates cytokinesis. Using cell-free systems from both frog eggs and humanExpand