Ya-lin Huang

  • Citations Per Year
Learn More
Ruscogenin (RUS), first isolated from Ruscus aculeatus, also a major steroidal sapogenin of traditional Chinese herb Radix Ophiopogon japonicus, has been found to exert significant anti-inflammatory and anti-thrombotic activities. Our previous studies suggested that ruscogenin remarkably inhibited adhesion of leukocytes to a human umbilical vein endothelial(More)
BACKGROUND Glaucoma is one of the leading causes of blindness in the world. Primary open-angle glaucoma (POAG) and primary congenital glaucoma (PCG) are subtypes of glaucoma. Myocillin is the first gene identified to be involved in POAG. Recently, myocillin mutation has been found in PCG. In this context, we reported a special glaucoma pedigree, which was(More)
AIM To construct the expression vector of small hairpin RNA (shRNA) and to investigate its efficacy in silencing nonmuscle myosin heavy chain IIA (MYH9)gene. METHODS According to the MYH9 cDNA sequence in GenBank, three shRNA expression vectors targeting MYH9 gene were constructed and were confirmed by digestion with restriction enzymes and DNA(More)
OBJECTIVE To study the effect of dexamethasone on trans epithelial electrical resistance (TEER) and the expression of AQP-1 in immortalized trabecular cells. METHODS Immortalized human trabecular cells were cultured on PET membrane in 24 wells plate. The cells were treated with Dexamethasone in concentration of 10(-7) mol/L. After the cultured cell became(More)
  • 1