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Dihydroartemisinin Regulates the Th/Treg Balance by Inducing Activated CD4+ T cell Apoptosis via Heme Oxygenase-1 Induction in Mouse Models of Inflammatory Bowel Disease
TLDR
DHA is a novel and valuable candidate for IBD therapy or Th/Treg immunoregulation and promoted heme oxygenase-1 (HO-1) production in vitro and in vivo, concomitant with CD4+ T cell apoptosis and restoration of the Th/ Treg balance.
Chamaejasmin B exerts anti-MDR effect in vitro and in vivo via initiating mitochondria-dependant intrinsic apoptosis pathway
  • Ya Wang, Qi Li, X. X. Zhu
  • Biology, Chemistry
    Drug design, development and therapy
  • 22 September 2015
TLDR
CHB exhibited good anti-MDR activity in vitro and in vivo, and the underlying mechanisms may be related to the activation of mitochondrial-dependant intrinsic apoptosis pathway.
Clinical study of impedance cardiography in rapid diagnosis of severe patients with dyspnea
TLDR
ICG diagnosis of patients with severe Dyspnea with superior sensitivity, specificity, positive predictive value and negative predictive value can help doctors quickly, effectively, and accurately diagnose the cause of dyspnea as cardiac or noncardiac.