Learn More
Nasopharyngeal carcinoma associated gene 6 (NGX6) is down-regulated in most colon cancer cell lines and tumor tissues when compared with their normal tissue samples. As a novel suppress tumor gene, it could inhibit colon cancer cell growth and cell cycle progression. However, little is known about the transcriptional mechanisms controlling NGX6 gene(More)
PURPOSE To assess the accuracy of 320-detector row nonsubtracted and subtracted volumetric computed tomographic (CT) angiography for detection of cerebral aneurysms. MATERIALS AND METHODS After institutional review board approval and informed written consent were obtained, 282 consecutive patients suspected of having cerebral aneurysms underwent CT(More)
Myosin light chain kinases (MLCK) phosphorylate the regulatory light chain of myosin II in thick filaments and bind to F-actin-containing thin filaments with high affinity. The ability of short myosin light chain kinase (S-MLCK) to bind F-actin is structurally attributed to the DFRXXL regions in its N-terminus. The long myosin light chain kinase (L-MLCK)(More)
The initiation, promotion and progression of human cancer are complex, polygenic, multi-factored processes. Through systematic proteomic analysis, different stages of CRC (colorectal cancer) biopsies were examined, and 199 differentially expressed proteins were detected between TNM (the tumor, nodes, and metastasis) stages I-IV and normal tissue (One-Way(More)
OBJECTIVE Many cases of subarachnoid hemorrhage are the result of rupture of small cerebral aneurysms. The aim of the study was to assess the diagnostic accuracy of 16-row multislice computed tomographic angiography (CTA) in detecting small cerebral aneurysms (<or=5 mm) compared with digital subtraction angiography (DSA), surgical findings, or both. (More)
OBJECT The goal of this study was to prospectively compare the effectiveness of 16-slice computed tomography (CT) angiography with that of conventional digital subtraction (DS) angiography and the surgical findings used to detect and characterize intracranial aneurysms. METHODS Two hundred forty-four consecutive patients underwent both CT angiography and(More)
OBJECTIVES The aim of the study is to assess the clinical value of 16-row multislice computed tomographic angiography (CTA) for detection and treatment of intracranial aneurysms. PATIENTS AND METHODS Between January 2005 and October 2008, 388 patients were included and successively underwent 16-slice CTA for suspected intracranial aneurysms. Three(More)
Colorectal cancer (CRC) is a common malignant gastrointestinal cancer. Efforts for preventive and personalized medicine have intensified in the last decade with attention to novel forms of biomarkers. In the present study, microRNA and genetic analyses were performed in tandem for differential transcriptome profiling between primary tumors with or without(More)
Glioma is regarded as the most prevalent malignant carcinoma of the central nervous system. Thus, the development of new therapeutic strategies targeting glioma is of significant clinical importance. Long non-coding RNAs (lncRNAs) are functional RNA molecules without a protein-coding function and are reportedly involved in the initiation and progression of(More)
Oxidored-nitro domain containing protein 1 (NOR1) gene is a novel nitroreductase gene first isolated from nasopharyngeal carcinoma (NPC). It plays an important role in the formation of chemical carcinogen and the carcinogenesis of NPC for its nitrosation function. Overexpression of the wild-type NOR1 gene in nasopharyngeal carcinoma cells is effective to(More)