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A novel N-succinyl chitosan(Suc-Chi)/alginate hydrogel bead was prepared by the ionic gelation method for the controlled delivery of nifedipine. The structure and surface morphology of the hydrogel were characterized by FTIR and SEM, respectively. Factors influencing the swelling ability of the hydrogel bead were also investigated, such as the ratio of(More)
Chitosan-alginate (CS/ALG) nanoparticles were prepared by ionotropic pre-gelation of an alginate core followed by chitosan polyelectrolyte complexation, nifedipine was chosen as a model drug. Morphology and structure characterization of nanoparticles were investigated by transmission electron microscope (TEM) and Fourier transform infrared spectra (FTIR),(More)
The aim of the present work was to investigate the swelling behavior and in vitro release of nifedipine from alginate-chitosan hydrogel beads. Structure and surface morphology of the hydrogel were characterized by FTIR and SEM, respectively. Alginate-chitosan mixed beads and alginate-chitosan coated beads were prepared by ionic gelation method. The swelling(More)
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