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OBJECT This study was designed to investigate the effect of treatment with a novel composite material consisting of embryonic neurospheres and bone marrow-derived stromal cell spheres (NMSCSs) in a rat model of traumatic brain injury (TBI). METHODS The NMSCS composite was injected into the TBI contusion site 24 hours after injury, and all rats were killed(More)
Understanding nonverbal behaviors in human machine interaction is a complex and challenge task. One of the key aspects is to recognize human emotion states accurately. This paper presents our effort to the Audio/Visual Emotion Challenge (AVEC'14), whose goal is to predict the continuous values of the emotion dimensions arousal, valence and dominance at each(More)
—Recent successes in learning-based image classification , however, heavily rely on the large number of annotated training samples, which may require considerable human efforts. In this paper, we propose a novel active learning framework, which is capable of building a competitive classifier with optimal feature representation via a limited amount of(More)
In service oriented grid environment, quality of service (QoS) support becomes more and more important. In this paper, we propose a QoS management framework which is based on class of service (CoS) for grid services, called CQEF. By using CoS instead of SLA in grid environment, grid service users and providers will no longer need to negotiate for a complex(More)
Peroxisome proliferator activated receptor alpha (PPARα) ameliorates ethanol induced hepatic steatohepatitis. However, its role in alcoholic liver fibrosis has not been fully clarified. The aim of this study was to elucidate the effect and the molecular basis of PPARα in ethanol induced liver fibrosis in mice. C57BL/6J mice were fed with 4%(More)
The authors investigated the effects of bilateral intrahippocampal co-injection of Abeta1-40 (4 microg for each side) with ibotenic acid (Ibo, 2 microg for each side) on rats' performance in the open field behavior, Y-maze, and passive avoidance task, and also examined some neurochemical changes in hippocampus two weeks after the co-injection. The results(More)
The present study was designed to investigate the effects of the intrahippocampal co-injection of beta-amyloid protein1-40 (Abeta(1-40)) with ibotenic acid (Ibo) on learning and memory in normal and aging model rats, and to explore the mechanism underlying the effects of the co-injection. The normal and aging rats were bilaterally injected Abeta(1-40) (4(More)
Keywords: Artificial Bee Colony algorithm (ABC) AB off-lattice model Protein secondary structure optimization Convergence of algorithm a b s t r a c t Predicting the secondary structure of protein has been the focus of scientific research for decades, but it remains to be a challenge in bioinformatics due to the increasing computation complexity. In this(More)
Myocarditis is a common cause of dilated cardiomyopathy leading to heart failure. Chronic stages of myocarditis may be initiated by autoimmune responses to exposed cardiac Ags after myocyte damage. Cardiac myosin, a heart autoantigen, induced experimental autoimmune myocarditis (EAM) in susceptible animals. Although cardiac myosin-induced myocarditis has(More)
To develop a stable chronic obstructive pulmonary disease (COPD) model in rats. Sprague-Dawley rats were treated with cigarette-smoke inhalation (CSI) for 12 weeks, repetitive bacterial infection (RBI) for 8 weeks, or the combination of the two (CCR) for 12 weeks and followed up for the additional 20 weeks. Tidal volume (V(T)), peak expiratory flow (PEF)(More)